protein

Flap endonuclease 1/FEN-1 Protein, Human (His, Myc)

HY-P700010

5 μg;10 μg;50 μg

65;110;350 USD

Flap endonuclease 1/FEN-1 Protein, Human (His, Myc)

Protein

E. coli

5 μg;10 μg;50 μg

65;110;350 USD

Flap endonuclease 1 (FEN-1) is a structure-specific nuclease crucial for DNA replication and repair. In replication, it cleaves 5'-overhanging flaps, guiding DNA polymerase and creating a nick for ligation. FEN-1 is integral to the long patch base excision repair pathway, preventing genomic instability. It exhibits 5'-3' exonuclease and RNase H activities, playing roles in rDNA and mitochondrial DNA replication and repair. Flap endonuclease 1/FEN-1 Protein, Human (His, Myc) is the recombinant human-derived Flap endonuclease 1/FEN-1 protein, expressed by E. coli , with N-10*His, C-Myc labeled tag.