protein

Cadherin-1/CD324 Protein, Mouse (HEK293, C-His)

HY-P700008

5 μg;10 μg;50 μg;100 μg

39;65;180;298 USD

Cadherin-1/CD324 Protein, Mouse (HEK293, C-His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

39;65;180;298 USD

Cadherin-1/CD324 is a calcium-dependent cell adhesion protein that orchestrates homogeneous interactions, promoting cell cohesion and potential cell type sorting. CDH1 regulates epithelial cell adhesion, mobility, and proliferation and acts as an invasive suppressor. Cadherin-1/CD324 Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-6*His labeled tag.

Mouse

Cadherin-1, also known as CD324, represents a group of calcium-dependent cell adhesion proteins that exhibit preferential homophilic interactions, fostering cohesion in connecting cells and potentially contributing to the sorting of heterogeneous cell types. CDH1 is intricately involved in the regulation of cell-cell adhesions, mobility, and proliferation of epithelial cells, playing a significant role as an invasive suppressor. Beyond its adhesion functions, CDH1 serves as a ligand for integrin alpha-E/beta-7, suggesting its involvement in diverse cellular processes. Notably, E-Cadherin/CTF2, a cleavage product of CDH1, contributes to the non-amyloidogenic degradation of Abeta precursors, exerting a strong inhibitory effect on the production of APP C99 and C83.

Cadherin-1; CDH1; CAM 120/80; E-cadherin; CD324

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.