product summary
company name :
MBL International
product type :
antibody
product name :
p62,sqstm1
catalog :
PM074
clonality :
polyclonal
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2000; loading ...; fig 2b
Jena K, Kolapalli S, Mehto S, Nath P, Das B, Sahoo P, et al. TRIM16 controls assembly and degradation of protein aggregates by modulating the p62-NRF2 axis and autophagy. EMBO J. 2018;37: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s7
  • western blot; mouse; loading ...; fig 4a
Ugun Klusek A, Tatham M, Elkharaz J, Constantin Teodosiu D, Lawler K, Mohamed H, et al. Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway. Cell Death Dis. 2017;8:e2531 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1c
  • western blot; human; loading ...; fig 1b
Watanabe Y, Tsujimura A, Taguchi K, Tanaka M. HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis. Autophagy. 2017;13:133-148 pubmed publisher
Cloer E, Siesser P, Cousins E, Goldfarb D, Mowrey D, Harrison J, et al. p62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2. Mol Cell Biol. 2018;38: pubmed publisher
Morita K, Hama Y, Izume T, Tamura N, Ueno T, Yamashita Y, et al. Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation. J Cell Biol. 2018;217:3817-3828 pubmed publisher
Yamada T, Murata D, Adachi Y, Itoh K, Kameoka S, Igarashi A, et al. Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease. Cell Metab. 2018;28:588-604.e5 pubmed publisher
Mizunoe Y, Kobayashi M, Sudo Y, Watanabe S, Yasukawa H, Natori D, et al. Trehalose protects against oxidative stress by regulating the Keap1-Nrf2 and autophagy pathways. Redox Biol. 2018;15:115-124 pubmed publisher
company information
MBL International
15A Constitution Way Woburn, MA 01801
customerservice@mblintl.com
http://www.mblintl.com
headquarters: United States