product summary
company name :
MBL International
product type :
antibody
product name :
Human LC3 Polyclonal Antibody
catalog :
PM036
clonality :
polyclonal
conjugate :
nonconjugated
reactivity :
Japanese rice fish, human, mouse, rat, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other
more info or order :
citations: 102
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 2b
Ikari S, Yang Q, Lu S, Liu Y, Hao F, Tong G, et al. Quercetin in Tartary Buckwheat Induces Autophagy against Protein Aggregations. Antioxidants (Basel). 2021;10: pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 6e
Yamamuro T, Nakamura S, Yamano Y, Endo T, Yanagawa K, Tokumura A, et al. Rubicon prevents autophagic degradation of GATA4 to promote Sertoli cell function. PLoS Genet. 2021;17:e1009688 pubmed publisher
  • western blot; Japanese rice fish; 1:2000; loading ...; fig 5a
Nakanishi E, Uemura N, Akiyama H, Kinoshita M, Masanori S, Taruno Y, et al. Impact of Gba2 on neuronopathic Gaucher's disease and α-synuclein accumulation in medaka (Oryzias latipes). Mol Brain. 2021;14:80 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 3f
  • western blot; human; 1:1000; loading ...; fig 3e
  • immunohistochemistry; mouse; 1:2000; loading ...; fig 6g
Wang Y, Lee Y, Hsu Y, Chiu I, Huang C, Huang C, et al. The Kidney-Related Effects of Polystyrene Microplastics on Human Kidney Proximal Tubular Epithelial Cells HK-2 and Male C57BL/6 Mice. Environ Health Perspect. 2021;129:57003 pubmed publisher
  • other; human; loading ...; fig s1h, s1l
Hess M, Krainer I, Filipek P, Witting B, Gutleben K, Vietor I, et al. Advanced Microscopy for Liver and Gut Ultrastructural Pathology in Patients with MVID and PFIC Caused by MYO5B Mutations. J Clin Med. 2021;10: pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 7a
Aoto K, Kato M, Akita T, Nakashima M, Mutoh H, Akasaka N, et al. ATP6V0A1 encoding the a1-subunit of the V0 domain of vacuolar H+-ATPases is essential for brain development in humans and mice. Nat Commun. 2021;12:2107 pubmed publisher
  • western blot; chicken; loading ...; fig 5
Chou P, Chen Y, Chung T, Walzem R, Lai L, Chen S. Supplemental 25-hydroxycholecalciferol Alleviates Inflammation and Cardiac Fibrosis in Hens. Int J Mol Sci. 2020;21: pubmed publisher
  • immunocytochemistry; human; loading ...; fig 3e
Yamano K, Kikuchi R, Kojima W, Hayashida R, Koyano F, Kawawaki J, et al. Critical role of mitochondrial ubiquitination and the OPTN-ATG9A axis in mitophagy. J Cell Biol. 2020;219: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3e
Boukhalfa A, Nascimbeni A, Ramel D, Dupont N, Hirsch E, Gayral S, et al. PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress. Nat Commun. 2020;11:294 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1a
Ye X, Zhu M, Che X, Wang H, Liang X, Wu C, et al. Lipopolysaccharide induces neuroinflammation in microglia by activating the MTOR pathway and downregulating Vps34 to inhibit autophagosome formation. J Neuroinflammation. 2020;17:18 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s5f
Zheng X, Yang Z, Gu Q, Xia F, Fu Y, Liu P, et al. The protease activity of human ATG4B is regulated by reversible oxidative modification. Autophagy. 2019;: pubmed publisher
  • western blot; human; 1:3000; loading ...; fig 3a
Gao L, Wang Z, Lu D, Huang J, Liu J, Hong L. Paeonol induces cytoprotective autophagy via blocking the Akt/mTOR pathway in ovarian cancer cells. Cell Death Dis. 2019;10:609 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1e
Pan H, Alamri A, Valapala M. Nutrient deprivation and lysosomal stress induce activation of TFEB in retinal pigment epithelial cells. Cell Mol Biol Lett. 2019;24:33 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1e
  • western blot; human; loading ...; fig 1a
Slobodnyuk K, Radic N, Ivanova S, Lladó A, Trempolec N, Zorzano A, et al. Autophagy-induced senescence is regulated by p38α signaling. Cell Death Dis. 2019;10:376 pubmed publisher
  • western blot; rat; 1:2000; loading ...; fig 8a
Pierzynowska K, Podlacha M, Gaffke L, Majkutewicz I, Mantej J, Wegrzyn A, et al. Autophagy-dependent mechanism of genistein-mediated elimination of behavioral and biochemical defects in the rat model of sporadic Alzheimer's disease. Neuropharmacology. 2019;148:332-346 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s2d
  • western blot; human; loading ...; fig s3a, s3b
Shi G, OZOG S, Torbett B, Compton A. mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3. Proc Natl Acad Sci U S A. 2018;115:E10069-E10078 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 1j
Jena K, Kolapalli S, Mehto S, Nath P, Das B, Sahoo P, et al. TRIM16 controls assembly and degradation of protein aggregates by modulating the p62-NRF2 axis and autophagy. EMBO J. 2018;37: pubmed publisher
  • immunocytochemistry; human; 1:250; loading ...; fig s4i
Gut G, Herrmann M, Pelkmans L. Multiplexed protein maps link subcellular organization to cellular states. Science. 2018;361: pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 2e
Hartlova A, Herbst S, Peltier J, Rodgers A, Bilkei Gorzo O, Fearns A, et al. LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages. EMBO J. 2018;37: pubmed publisher
  • immunocytochemistry; human; 1:3000; loading ...; fig 1d
Hsu C, Lee E, Gordon K, Paz E, Shen W, Ohnishi K, et al. MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB. Nat Commun. 2018;9:942 pubmed publisher
  • western blot; human; loading ...; fig 2a
Pei G, Buijze H, Liu H, Moura Alves P, Goosmann C, Brinkmann V, et al. The E3 ubiquitin ligase NEDD4 enhances killing of membrane-perturbing intracellular bacteria by promoting autophagy. Autophagy. 2017;13:2041-2055 pubmed publisher
  • western blot; human; loading ...; fig 3c
Sorokina I, Denisenko T, Imreh G, Tyurin Kuzmin P, Kaminskyy V, Gogvadze V, et al. Involvement of autophagy in the outcome of mitotic catastrophe. Sci Rep. 2017;7:14571 pubmed publisher
  • western blot; human; loading ...; fig 1d
Wei J, Xu H, Meng W. Noncentrosomal microtubules regulate autophagosome transport through CAMSAP2-EB1 cross-talk. FEBS Lett. 2017;591:2379-2393 pubmed publisher
  • flow cytometry; human; loading ...; fig ev6a
  • immunocytochemistry; human; loading ...; fig ev6b
Monel B, Compton A, Bruel T, Amraoui S, Burlaud Gaillard J, Roy N, et al. Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells. EMBO J. 2017;36:1653-1668 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 2d
Hubber A, Kubori T, Coban C, Matsuzawa T, Ogawa M, Kawabata T, et al. Bacterial secretion system skews the fate of Legionella-containing vacuoles towards LC3-associated phagocytosis. Sci Rep. 2017;7:44795 pubmed publisher
  • western blot; mouse; loading ...; fig 2b
Kissing S, Rudnik S, Damme M, Lüllmann Rauch R, Ichihara A, Kornak U, et al. Disruption of the vacuolar-type H+-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes. Autophagy. 2017;13:670-685 pubmed publisher
  • western blot; human; loading ...; fig 4b
Kondo H, Maksimova N, Otomo T, Kato H, Imai A, Asano Y, et al. Mutation in VPS33A affects metabolism of glycosaminoglycans: a new type of mucopolysaccharidosis with severe systemic symptoms. Hum Mol Genet. 2017;26:173-183 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 7d
Watanabe Y, Tsujimura A, Taguchi K, Tanaka M. HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis. Autophagy. 2017;13:133-148 pubmed publisher
  • immunocytochemistry; human; fig 5c
Elgner F, Ren H, Medvedev R, Ploen D, Himmelsbach K, Boller K, et al. The Intracellular Cholesterol Transport Inhibitor U18666A Inhibits the Exosome-Dependent Release of Mature Hepatitis C Virus. J Virol. 2016;90:11181-11196 pubmed
  • western blot; human; loading ...; fig 2b
Chan S, Lee J, Narula M, Ou J. Suppression of Host Innate Immune Response by Hepatitis C Virus via Induction of Autophagic Degradation of TRAF6. J Virol. 2016;90:10928-10935 pubmed publisher
  • western blot; human; loading ...; fig 2a
Zhang Q, Jin R, Zhang X, Sheng J, Yu F, Tan R, et al. The putative oncotarget CSN5 controls a transcription-uncorrelated p53-mediated autophagy implicated in cancer cell survival under curcumin treatment. Oncotarget. 2016;7:69688-69702 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 3b
  • western blot; human; loading ...; fig 3a
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s10a
Xie N, Yuan K, Zhou L, Wang K, Chen H, Lei Y, et al. PRKAA/AMPK restricts HBV replication through promotion of autophagic degradation. Autophagy. 2016;12:1507-20 pubmed publisher
  • western blot; human; fig 5
Li Q, Karim A, Ding X, Das B, Dobrowolski C, Gibson R, et al. Novel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosis. Sci Rep. 2016;6:27566 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 6b
  • western blot; mouse; loading ...; fig 6a
Li W, Jin D, Hata M, Takai S, Yamanishi K, Shen W, et al. Dysfunction of mitochondria and deformed gap junctions in the heart of IL-18-deficient mice. Am J Physiol Heart Circ Physiol. 2016;311:H313-25 pubmed publisher
  • immunocytochemistry; human; fig 1
  • immunocytochemistry; mouse; fig 1
Nakamura T, Furukawa A, Uchida K, Ogawa T, Tamura T, Sakonishi D, et al. Autophagy Induced by Intracellular Infection of Propionibacterium acnes. PLoS ONE. 2016;11:e0156298 pubmed publisher
  • western blot; human; fig 4
Zhang J, Lachance V, Schaffner A, Li X, Fedick A, Kaye L, et al. A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects. PLoS Genet. 2016;12:e1005848 pubmed publisher
  • immunocytochemistry; mouse; fig 4
Zhuang H, Tian W, Li W, Zhang X, Wang J, Yang Y, et al. Autophagic Cell Death and Apoptosis Jointly Mediate Cisatracurium Besylate-Induced Cell Injury. Int J Mol Sci. 2016;17:515 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 2h
  • western blot; mouse; loading ...; fig 2d
Ding Y, Adachi H, Katsuno M, Sahashi K, Kondo N, Iida M, et al. BIIB021, a synthetic Hsp90 inhibitor, induces mutant ataxin-1 degradation through the activation of heat shock factor 1. Neuroscience. 2016;327:20-31 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 7a
Park J, Jung C, Seo M, Otto N, Grunwald D, Kim K, et al. The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14. Autophagy. 2016;12:547-64 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:2000; fig 1
  • western blot; mouse; 1:1000; fig 1
Giannogonas P, Apostolou A, Manousopoulou A, Theocharis S, Macari S, Psarras S, et al. Identification of a novel interaction between corticotropin releasing hormone (Crh) and macroautophagy. Sci Rep. 2016;6:23342 pubmed publisher
  • western blot; human; 1:10,000; fig 1
Tokuda E, Brännström T, Andersen P, Marklund S. Low autophagy capacity implicated in motor system vulnerability to mutant superoxide dismutase. Acta Neuropathol Commun. 2016;4:6 pubmed publisher
  • western blot; mouse; fig s1
Korwitz A, Merkwirth C, Richter Dennerlein R, Tröder S, Sprenger H, Quirós P, et al. Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria. J Cell Biol. 2016;212:157-66 pubmed publisher
  • immunocytochemistry; mouse; fig 6
  • western blot; mouse; fig 6
Cherepkova M, Sineva G, Pospelov V. Leukemia inhibitory factor (LIF) withdrawal activates mTOR signaling pathway in mouse embryonic stem cells through the MEK/ERK/TSC2 pathway. Cell Death Dis. 2016;7:e2050 pubmed publisher
  • western blot; human; fig s4
Puvirajesinghe T, Bertucci F, Jain A, Scerbo P, Belotti E, Audebert S, et al. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer. Nat Commun. 2016;7:10318 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig s5
Ruegsegger C, Stucki D, Steiner S, Angliker N, Radecke J, Keller E, et al. Impaired mTORC1-Dependent Expression of Homer-3 Influences SCA1 Pathophysiology. Neuron. 2016;89:129-46 pubmed publisher
Oe Y, Kakuda K, Yoshimura S, Hara N, Hasegawa J, Terawaki S, et al. PACSIN1 is indispensable for amphisome-lysosome fusion during basal autophagy and subsets of selective autophagy. PLoS Genet. 2022;18:e1010264 pubmed publisher
Lin Y, Huang C, Gao H, Li X, Lin Q, Zhou S, et al. AMBRA1 promotes dsRNA- and virus-induced apoptosis through interacting with and stabilizing MAVS. J Cell Sci. 2022;135: pubmed publisher
Sønstevold T, Engedal N, Torgersen M. Perturbation of Cellular Redox Homeostasis Dictates Divergent Effects of Polybutyl Cyanoacrylate (PBCA) Nanoparticles on Autophagy. Cells. 2021;10: pubmed publisher
Peng S, Chen X, Chen S, Zhang J, Wang C, Liu W, et al. Phase separation of Nur77 mediates celastrol-induced mitophagy by promoting the liquidity of p62/SQSTM1 condensates. Nat Commun. 2021;12:5989 pubmed publisher
Lopresti M, Cui W, Abernathy B, Fredrickson G, Barrow F, Desai A, et al. Hepatic lysosomal acid lipase overexpression worsens hepatic inflammation in mice fed a Western diet. J Lipid Res. 2021;62:100133 pubmed publisher
Deitersen J, Berning L, Stuhldreier F, Ceccacci S, Schlütermann D, Friedrich A, et al. High-throughput screening for natural compound-based autophagy modulators reveals novel chemotherapeutic mode of action for arzanol. Cell Death Dis. 2021;12:560 pubmed publisher
Silwal P, Kim J, Jeon S, Lee J, Kim Y, Kim Y, et al. Mitofusin-2 boosts innate immunity through the maintenance of aerobic glycolysis and activation of xenophagy in mice. Commun Biol. 2021;4:548 pubmed publisher
Hać A, Pierzynowska K, Herman Antosiewicz A. S6K1 Is Indispensible for Stress-Induced Microtubule Acetylation and Autophagic Flux. Cells. 2021;10: pubmed publisher
Wang J, Liu B, Xu Y, Yang M, Wang C, Song M, et al. Activation of CREB-mediated autophagy by thioperamide ameliorates β-amyloid pathology and cognition in Alzheimer's disease. Aging Cell. 2021;20:e13333 pubmed publisher
Li T, Kong L, Li X, Wu S, Attri K, Li Y, et al. Listeria monocytogenes upregulates mitochondrial calcium signalling to inhibit LC3-associated phagocytosis as a survival strategy. Nat Microbiol. 2021;6:366-379 pubmed publisher
Yan J, Huang J, Liu A, Wu J, Fan H, Shen M, et al. Atorvastatin improves motor function, anxiety and depression by NOX2-mediated autophagy and oxidative stress in MPTP-lesioned mice. Aging (Albany NY). 2020;13:831-845 pubmed publisher
Kobayashi M, Yasukawa H, Arikawa T, Deguchi Y, Mizushima N, Sakurai M, et al. Trehalose induces SQSTM1/p62 expression and enhances lysosomal activity and antioxidative capacity in adipocytes. FEBS Open Bio. 2020;: pubmed publisher
Bernard E, Fearns A, Bussi C, Santucci P, Peddie C, Lai R, et al. M. tuberculosis infection of human iPSC-derived macrophages reveals complex membrane dynamics during xenophagy evasion. J Cell Sci. 2020;134: pubmed publisher
Chen C, Lin C, Wu Y, Yen C, Huang Y, Lin J, et al. Lactulose and Melibiose Inhibit α-Synuclein Aggregation and Up-Regulate Autophagy to Reduce Neuronal Vulnerability. Cells. 2020;9: pubmed publisher
Leidal A, Huang H, Marsh T, Solvik T, Zhang D, Ye J, et al. The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles. Nat Cell Biol. 2020;22:187-199 pubmed publisher
Omi J, Watanabe Takahashi M, Igai K, Shimizu E, Tseng C, Miyasaka T, et al. The inducible amphisome isolates viral hemagglutinin and defends against influenza A virus infection. Nat Commun. 2020;11:162 pubmed publisher
Scotto Rosato A, Montefusco S, Soldati C, Di Paola S, Capuozzo A, Monfregola J, et al. TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway. Nat Commun. 2019;10:5630 pubmed publisher
Jia J, Claude Taupin A, Gu Y, Choi S, Peters R, Bissa B, et al. Galectin-3 Coordinates a Cellular System for Lysosomal Repair and Removal. Dev Cell. 2019;: pubmed publisher
Pasquier A, Vivot K, Erbs E, Spiegelhalter C, Zhang Z, Aubert V, et al. Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes. Nat Commun. 2019;10:3312 pubmed publisher
Di Rienzo M, Antonioli M, Fusco C, Liu Y, Mari M, Orhon I, et al. Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chains. Sci Adv. 2019;5:eaau8857 pubmed publisher
Kenny T, Craig A, Villanueva A, Germain D. Mitohormesis Primes Tumor Invasion and Metastasis. Cell Rep. 2019;27:2292-2303.e6 pubmed publisher
Wang B, Maxwell B, Joo J, Gwon Y, Messing J, Mishra A, et al. ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97. Mol Cell. 2019;74:742-757.e8 pubmed publisher
Valverde D, Yu S, Boggavarapu V, Kumar N, Lees J, Walz T, et al. ATG2 transports lipids to promote autophagosome biogenesis. J Cell Biol. 2019;218:1787-1798 pubmed publisher
Zhang X, Wang L, Ireland S, Ahat E, Li J, Bekier Ii M, et al. GORASP2/GRASP55 collaborates with the PtdIns3K UVRAG complex to facilitate autophagosome-lysosome fusion. Autophagy. 2019;:1-14 pubmed publisher
Kumar S, Gu Y, Abudu Y, Bruun J, Jain A, Farzam F, et al. Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation. Dev Cell. 2019;: pubmed publisher
Horos R, Büscher M, Kleinendorst R, Alleaume A, Tarafder A, Schwarzl T, et al. The Small Non-coding Vault RNA1-1 Acts as a Riboregulator of Autophagy. Cell. 2019;176:1054-1067.e12 pubmed publisher
Suvorova I, Knyazeva A, Petukhov A, Aksenov N, Pospelov V. Resveratrol enhances pluripotency of mouse embryonic stem cells by activating AMPK/Ulk1 pathway. Cell Death Discov. 2019;5:61 pubmed publisher
Hoffmann S, Orlando M, Andrzejak E, Bruns C, Trimbuch T, Rosenmund C, et al. Light-Activated ROS Production Induces Synaptic Autophagy. J Neurosci. 2019;39:2163-2183 pubmed publisher
Wang R, Tan J, Chen T, Han H, Tian R, Tan Y, et al. ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome-lysosome fusion. J Cell Biol. 2019;218:267-284 pubmed publisher
Kochetkova E, Blinova G, Bystrova O, Martynova M, Pospelov V, Pospelova T. Suppression of mTORC1 activity in senescent Ras-transformed cells neither restores autophagy nor abrogates apoptotic death caused by inhibition of MEK/ERK kinases. Aging (Albany NY). 2018;10:3574-3589 pubmed publisher
Abdullah A, Zhang M, Frugier T, Bedoui S, Taylor J, Crack P. STING-mediated type-I interferons contribute to the neuroinflammatory process and detrimental effects following traumatic brain injury. J Neuroinflammation. 2018;15:323 pubmed publisher
Janssen A, Katrukha E, van Straaten W, Verlhac P, Reggiori F, Kapitein L. Probing aggrephagy using chemically-induced protein aggregates. Nat Commun. 2018;9:4245 pubmed publisher
Kim J, Kim Y, Lee H, Jin H, Neupane C, Kim S, et al. GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections. Nat Commun. 2018;9:4184 pubmed publisher
Jiao Y, Wu L, Xue D, Liu X, Tian Z, Jiang S, et al. Marsdenia tenacissima extract induces apoptosis and suppresses autophagy through ERK activation in lung cancer cells. Cancer Cell Int. 2018;18:149 pubmed publisher
Fu Y, Hong L, Xu J, Zhong G, Gu Q, Gu Q, et al. Discovery of a small molecule targeting autophagy via ATG4B inhibition and cell death of colorectal cancer cells in vitro and in vivo. Autophagy. 2018;:1-17 pubmed publisher
Chen B, Zheng Y, Zhang J. Comparative Study of Different Diets-Induced NAFLD Models of Zebrafish. Front Endocrinol (Lausanne). 2018;9:366 pubmed publisher
Yamada T, Murata D, Adachi Y, Itoh K, Kameoka S, Igarashi A, et al. Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease. Cell Metab. 2018;28:588-604.e5 pubmed publisher
Alvarez Garcia O, Matsuzaki T, Olmer M, Miyata K, Mokuda S, Sakai D, et al. FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration. Aging Cell. 2018;17:e12800 pubmed publisher
Muñoz Galdeano T, Reigada D, Del Águila A, Velez I, Caballero López M, Maza R, et al. Cell Specific Changes of Autophagy in a Mouse Model of Contusive Spinal Cord Injury. Front Cell Neurosci. 2018;12:164 pubmed publisher
Moll F, Walter M, Rezende F, Helfinger V, Vasconez E, De Oliveira T, et al. NoxO1 Controls Proliferation of Colon Epithelial Cells. Front Immunol. 2018;9:973 pubmed publisher
Hallett P, Huebecker M, Brekk O, Moloney E, Rocha E, Priestman D, et al. Glycosphingolipid levels and glucocerebrosidase activity are altered in normal aging of the mouse brain. Neurobiol Aging. 2018;67:189-200 pubmed publisher
Jia J, Abudu Y, Claude Taupin A, Gu Y, Kumar S, Choi S, et al. Galectins Control mTOR in Response to Endomembrane Damage. Mol Cell. 2018;70:120-135.e8 pubmed publisher
Sun Y, Huang Y, Huang F, Mei W, Liu Q, Wang C, et al. 3'-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells. Theranostics. 2018;8:2044-2060 pubmed publisher
Pan P, Zhang H, Su L, Wang X, Liu D. Melatonin Balance the Autophagy and Apoptosis by Regulating UCP2 in the LPS-Induced Cardiomyopathy. Molecules. 2018;23: pubmed publisher
Chu J, Fu Y, Xu J, Zheng X, Gu Q, Luo X, et al. ATG4B inhibitor FMK-9a induces autophagy independent on its enzyme inhibition. Arch Biochem Biophys. 2018;644:29-36 pubmed publisher
Pierzynowska K, Gaffke L, Hać A, Mantej J, Niedziałek N, Brokowska J, et al. Correction of Huntington's Disease Phenotype by Genistein-Induced Autophagy in the Cellular Model. Neuromolecular Med. 2018;20:112-123 pubmed publisher
Mizunoe Y, Kobayashi M, Sudo Y, Watanabe S, Yasukawa H, Natori D, et al. Trehalose protects against oxidative stress by regulating the Keap1-Nrf2 and autophagy pathways. Redox Biol. 2018;15:115-124 pubmed publisher
Wallot Hieke N, Verma N, Schlütermann D, Berleth N, Deitersen J, Böhler P, et al. Systematic analysis of ATG13 domain requirements for autophagy induction. Autophagy. 2018;14:743-763 pubmed publisher
Kochetkova E, Blinova G, Bystrova O, Martynova M, Pospelov V, Pospelova T. Targeted elimination of senescent Ras-transformed cells by suppression of MEK/ERK pathway. Aging (Albany NY). 2017;9:2352-2375 pubmed publisher
Hong Z, Pedersen N, Wang L, Torgersen M, Stenmark H, Raiborg C. PtdIns3P controls mTORC1 signaling through lysosomal positioning. J Cell Biol. 2017;216:4217-4233 pubmed publisher
Shibutani S, Okazaki H, Iwata H. Dynamin-dependent amino acid endocytosis activates mechanistic target of rapamycin complex 1 (mTORC1). J Biol Chem. 2017;292:18052-18061 pubmed publisher
Raulien N, Friedrich K, Strobel S, Rubner S, Baumann S, von Bergen M, et al. Fatty Acid Oxidation Compensates for Lipopolysaccharide-Induced Warburg Effect in Glucose-Deprived Monocytes. Front Immunol. 2017;8:609 pubmed publisher
Kim T, Shin Y, Lee H, Kim J, Choe J, Jang J, et al. Ohmyungsamycins promote antimicrobial responses through autophagy activation via AMP-activated protein kinase pathway. Sci Rep. 2017;7:3431 pubmed publisher
Cho J, Kim S, Seo Y, Park S, Park B, Kim J, et al. The p90 ribosomal S6 kinase-UBR5 pathway controls Toll-like receptor signaling via miRNA-induced translational inhibition of tumor necrosis factor receptor-associated factor 3. J Biol Chem. 2017;292:11804-11814 pubmed publisher
Sahu S, Kumar M, Chakraborty S, Banerjee S, Kumar R, Gupta P, et al. MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBPβ regulate innate immune signaling, the polarization of macrophages and the trafficking of Mycobacterium tuberculosis to lysosomes during infection. PLoS Pathog. 2017;13:e1006410 pubmed publisher
Mizunoe Y, Sudo Y, Okita N, Hiraoka H, Mikami K, Narahara T, et al. Involvement of lysosomal dysfunction in autophagosome accumulation and early pathologies in adipose tissue of obese mice. Autophagy. 2017;13:642-653 pubmed publisher
Chauhan S, Kumar S, Jain A, Ponpuak M, Mudd M, Kimura T, et al. TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis. Dev Cell. 2016;39:13-27 pubmed publisher
company information
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