product summary
company name :
MBL International
product type :
antibody
product name :
LC3 Polyclonal Antibody
catalog :
PD014
clonality :
polyclonal
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; rat; 1:500; loading ...; fig 7a
  • immunohistochemistry; rat; 1:500; loading ...; fig 7d
  • western blot; rat; 1:1000; loading ...; fig 8b
Moreno Blas D, Gorostieta Salas E, Pommer Alba A, Muciño Hernández G, Gerónimo Olvera C, Maciel Barón L, et al. Cortical neurons develop a senescence-like phenotype promoted by dysfunctional autophagy. Aging (Albany NY). 2019;11:6175-6198 pubmed publisher
  • western blot; human; loading ...; fig 4f
Potes Y, de Luxán Delgado B, Rodríguez González S, Guimarães M, Solano J, Fernández Fernández M, et al. Overweight in elderly people induces impaired autophagy in skeletal muscle. Free Radic Biol Med. 2017;110:31-41 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig s6c
Lee C, Hanna A, Wang H, Dagnino Acosta A, Joshi A, Knoblauch M, et al. A chemical chaperone improves muscle function in mice with a RyR1 mutation. Nat Commun. 2017;8:14659 pubmed publisher
  • western blot; human; fig s2a
Seo B, Min K, Woo S, Choe M, Choi K, Lee Y, et al. Inhibition of Cathepsin S Induces Mitochondrial ROS That Sensitizes TRAIL-Mediated Apoptosis Through p53-Mediated Downregulation of Bcl-2 and c-FLIP. Antioxid Redox Signal. 2017;27:215-233 pubmed publisher
  • western blot; mouse; fig 7
Kim S, Choi K, Cho S, Yun S, Jeon J, Koh Y, et al. Fisetin stimulates autophagic degradation of phosphorylated tau via the activation of TFEB and Nrf2 transcription factors. Sci Rep. 2016;6:24933 pubmed publisher
  • western blot; human; fig 5
Nyhan M, O Donovan T, Boersma A, Wiemer E, McKenna S. MiR-193b promotes autophagy and non-apoptotic cell death in oesophageal cancer cells. BMC Cancer. 2016;16:101 pubmed publisher
  • western blot; mouse; fig 5c
Zhou Q, Yen A, Rymarczyk G, Asai H, Trengrove C, Aziz N, et al. Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease. Nat Commun. 2016;7:10332 pubmed publisher
Lizama B, Palubinsky A, Raveendran V, Moore A, Federspiel J, Codreanu S, et al. Neuronal Preconditioning Requires the Mitophagic Activity of C-terminus of HSC70-Interacting Protein. J Neurosci. 2018;38:6825-6840 pubmed publisher
Lassak A, Dean M, Wyczechowska D, Wilk A, Marrero L, Trillo Tinoco J, et al. Molecular and Structural Traits of Insulin Receptor Substrate 1/LC3 Nuclear Structures and Their Role in Autophagy Control and Tumor Cell Survival. Mol Cell Biol. 2018;38: pubmed publisher
Iwashita H, Sakurai H, Nagahora N, Ishiyama M, Shioji K, Sasamoto K, et al. Small fluorescent molecules for monitoring autophagic flux. FEBS Lett. 2018;592:559-567 pubmed publisher
Baron O, Boudi A, Dias C, Schilling M, Nölle A, Vizcay Barrena G, et al. Stall in Canonical Autophagy-Lysosome Pathways Prompts Nucleophagy-Based Nuclear Breakdown in Neurodegeneration. Curr Biol. 2017;27:3626-3642.e6 pubmed publisher
Moruno Manchon J, Uzor N, Kesler S, Wefel J, Townley D, Nagaraja A, et al. TFEB ameliorates the impairment of the autophagy-lysosome pathway in neurons induced by doxorubicin. Aging (Albany NY). 2016;8:3507-3519 pubmed publisher
Feng Y, Cui Y, Gao J, Li M, Li R, Jiang X, et al. Resveratrol attenuates neuronal autophagy and inflammatory injury by inhibiting the TLR4/NF-κB signaling pathway in experimental traumatic brain injury. Int J Mol Med. 2016;37:921-30 pubmed publisher
Zhang X, Zhang T, Song D, Zhou J, Han R, Qin Z, et al. Endoplasmic reticulum chaperone GRP78 is involved in autophagy activation induced by ischemic preconditioning in neural cells. Mol Brain. 2015;8:20 pubmed publisher
company information
MBL International
15A Constitution Way Woburn, MA 01801
customerservice@mblintl.com
http://www.mblintl.com
headquarters: United States