anti-human Perforin mAbs Pf-80/164, purified | MABTECH 3465-3-1000 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MABTECH

product type :

antibody

product name :

anti-human Perforin mAbs Pf-80/164, purified

catalog :

3465-3-1000

quantity :

2 mg

price :

710 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

Pf-80/164

reactivity :

human

citations: 10

Reference
Hu X, Valentin A, Cai Y, Dayton F, Rosati M, Ramirez Salazar E, et al. DNA-vaccine induced long-lasting cytotoxic T cells targeting conserved elements of HIV Gag are boosted upon DNA or rMVA vaccination. Hum Gene Ther. 2018;: pubmed publisher
Parrot T, Allard M, Oger R, Benlalam H, Raingeard de la Blétière D, Coutolleau A, et al. IL-9 promotes the survival and function of human melanoma-infiltrating CD4(+) CD8(+) double-positive T cells. Eur J Immunol. 2016;46:1770-82 pubmed publisher
Kim S, Saide K, Farrell J, Faulkner L, Tailor A, Ogese M, et al. Characterization of amoxicillin- and clavulanic acid-specific T cells in patients with amoxicillin-clavulanate-induced liver injury. Hepatology. 2015;62:887-99 pubmed publisher
Wilkinson K, Walker N, Meintjes G, Deffur A, Nicol M, Skolimowska K, et al. Cytotoxic mediators in paradoxical HIV-tuberculosis immune reconstitution inflammatory syndrome. J Immunol. 2015;194:1748-54 pubmed publisher
Gudmundsdotter L, Wahren B, Haller B, Boberg A, Edback U, Bernasconi D, et al. Amplified antigen-specific immune responses in HIV-1 infected individuals in a double blind DNA immunization and therapy interruption trial. Vaccine. 2011;29:5558-66 pubmed publisher
Snyder Cappione J, Tincati C, Eccles James I, Cappione A, Ndhlovu L, Koth L, et al. A comprehensive ex vivo functional analysis of human NKT cells reveals production of MIP1-? and MIP1-?, a lack of IL-17, and a Th1-bias in males. PLoS ONE. 2010;5:e15412 pubmed publisher
Osada T, Hsu D, Hammond S, Hobeika A, Devi G, Clay T, et al. Metastatic colorectal cancer cells from patients previously treated with chemotherapy are sensitive to T-cell killing mediated by CEA/CD3-bispecific T-cell-engaging BiTE antibody. Br J Cancer. 2010;102:124-33 pubmed publisher
Chung W, Hung S, Yang J, Su S, Huang S, Wei C, et al. Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis. Nat Med. 2008;14:1343-50 pubmed publisher
Zuber B, Quigley M, Critchfield J, Shacklett B, Abel K, Miller C, et al. Detection of macaque perforin expression and release by flow cytometry, immunohistochemistry, ELISA, and ELISpot. J Immunol Methods. 2006;312:45-53 pubmed
Adhikary D, Behrends U, Moosmann A, Witter K, Bornkamm G, Mautner J. Control of Epstein-Barr virus infection in vitro by T helper cells specific for virion glycoproteins. J Exp Med. 2006;203:995-1006 pubmed

product information

Product Code :

3465-3-1000

Product Name :

anti-human Perforin mAbs Pf-80/164, purified

Categories :

Antibodies

Size :

2 mg

Size Number :

Size Unit :

EUR :

710

USD :

710 USD

GBP :

490

AUD :

1070

SEK :

5515

Antibody-Clone :

Pf-80/164

Enzyme/Conjugate :

unconjugated

Format :

purified

Application :

ELISpot, ELISA

Reactivities :

human, non-human primates

Analytes :

Perforin

Host :

Mouse

Isotype :

IgG1

Specificity :

Native Perforin.

Complementary Products :

3465-6-1000, 3310-9-1000

Contents :

Pf-80/164, purified, supplied at 1 mg/ml in PBS with 0.02% sodium azide

Product Header :

Monoclonal antibodies specific for Perforin

Description 1 :

These monoclonal antibodies enable sensitive and specific detection of human Perforin in immunoassays such as ELISA and ELISpot.

Description 2 :

We recommend Pf-80/164 as capture antibodies in human Perforin ELISA and ELISpot in combination with biotinylated detection antibody Pf-344.

Species Cross Reactivities :

The monoclonal antibody cross-reacts with Perforin from non-human primates.

References :

Adhikary, D., et al. (2006). Control of Epstein-Barr virus infection in vitro by T helper cells specific for virion glycoproteins. The Journal of experimental medicine. (http://www.ncbi.nlm.nih.gov/pubmed/16549597) Parrot, T., et al. (2016). IL-9 promotes the survival and function of human melanoma - infiltrating CD4 CD8 double-positive T cells. European journal of immunology. (http://www.ncbi.nlm.nih.gov/pubmed/27094152) Chung, W. H., et al. (2008). Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis. Nature medicine. (http://www.ncbi.nlm.nih.gov/pubmed/19029983) Gudmundsdotter, L., et al. (2011). Amplified antigen-specific immune responses in HIV-1 infected individuals in a double blind DNA immunization and therapy interruption trial. Vaccine. (http://www.ncbi.nlm.nih.gov/pubmed/21300092) Hu, X., et al. (2018). DNA-vaccine induced long-lasting cytotoxic T cells targeting conserved elements of HIV Gag are boosted upon DNA or rMVA vaccination. Hum Gene Ther. (http://www.ncbi.nlm.nih.gov/pubmed/29869530)

Shelf Life :

18 months

Last updated :

2013-07-01