This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
protein
product name :
Mouse TGFB1 / TGF Beta 1 Protein (Recombinant His) - LS-G3147
catalog :
LS-G3147
product information
ProteinId :
3147
CatalogNumber :
LS-G3147
Product Name :
Mouse TGFB1 / TGF Beta 1 Protein (Recombinant His) - LS-G3147
Description :
Members of the Transforming growth factor beta (TGFB) family of cytokines are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. TGFB1 is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. Recombinant mouse TGFB1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
PresentationDesc :
20 mM Tris-HCl, pH 8.0, 10% Glycerol
ProteinTag :
His
ProteinType :
Recombinant
ProteinSpecies :
Mouse
ProteinSourceSpecies :
E. coli
RecommendedStorage :
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.
Purification :
Greater than 85% by SDS-PAGE
Gene :
TGFB1 / TGF Beta 1
StandardGeneSymbol :
TGFB1
gene family :
TGF beta
Synonyms :
TGFB1, CED, DPD1, Diaphyseal dysplasia 1, LAP, Latency-associated peptide, TGF Beta, TGFbeta, TGF-beta 1 protein, TGF-beta-1, TGFB
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.