protein

Rat CXCL7 / PPBP Protein (Recombinant) - LS-G27300

LS-G27300

LS-G27300

Rat CXCL7 / PPBP Protein (Recombinant) - LS-G27300

Thymus Chemokine-1, also called Chemokine (C-X-C motif) ligand 7 (CXCL7) , is a member of the CXC chemokines. Similar to other ELR domain containing CXC chemokines such as IL-8 and the GRO proteins, Thymus Chemokine-1 has been shown to bind CXCR-2 and be a chemoattractant forneutrophils and play a role in their activation. Although CTAP-III, Beta-TG and PBP represent amino-terminal extended variants of Thymus Chemokine-1 and possess the same CXC chemokine domains, these proteins do not exhibit Thymus Chemokine-1 activity. Recently, it has been shown that the additional amino-terminal residues of CTAP-III mask the critical ELR receptor binding domain that is exposed on Thymus Chemokine-1 and may account for lack of Thymus Chemokine-1 activity. Rat CXCL7 shares 72% amino acid sequence identity with mouse CXCL7. Recombinant rat Thymus Chemokine-1/ CXCL7 produced in CHO cells is a polypeptide chain containing 62 amino acids. A fully biologically active molecule, rrThymus Chemokine-1/CXCL7 has a molecular mass of 9.8 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.

Lyophilized from PBS

Recombinant

Rat

Hamster-Chinese

Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 3 months.

Reconstitute using ddH2O or PBS at 100 µg/ml

Greater than 97% by SDS-PAGE and HPLC

9.8 kDa (SDS-PAGE)

CXCL7 / PPBP

PPBP

Intercrine alpha

Intercrine

PPBP, Beta-thromboglobulin, B-TG1, Beta-TG, C-X-C motif chemokine 7, CTAP3, CXCL7, CTAP-III, CXC chemokine ligand 7, NAP-2, NAP-2-L1, PBP, LA-PF4, LDGF, SCYB7, Small-inducible cytokine B7, Small inducible cytokine B7, THBGB1, Thrombocidin 2, TC2, TGB, Thrombocidin 1, Thromboglobulin, beta-1, CTAPIII, MDGF, Platelet basic protein, SCAR10, TC1, THBGB

Worldwide