This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
protein
product name :
IL-1B / IL-1 Beta Protein (Recombinant) (Ala115-Pro267) - LS-G27298
catalog :
LS-G27298
product information
ProteinId :
27298
CatalogNumber :
LS-G27298
Product Name :
IL-1B / IL-1 Beta Protein (Recombinant) (Ala115-Pro267) - LS-G27298
Description :
Interleukin-1 beta (rpIL-1Beta) is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. IL-1a and IL-1Beta are structurally related polypeptides that share approximately 27% amino acid (aa) identity in porcine. While IL-1a and IL-1Beta are regulated independently, they bind to the same receptor and exert identical biological effects. IL-1Beta stimulates thymocyte proliferation by inducing il-2 release, b-cell maturation and proliferation, and fibroblast growth factor activity.Recombinant Porcine IL-1Beta produced in E. coli is a single non-glycosylated polypeptide chain containing 154 amino acids. A fully biologically active molecule, rpIL-1Beta has a molecular mass of 17.7 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
PresentationDesc :
Lyophilized from PBS
ProteinType :
Recombinant
ProteinSourceSpecies :
E. coli
RecommendedStorage :
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 3 months.
Purification :
Greater than 95% by SDS-PAGE
PredictedMolecularWeight :
17.7 kDa (SDS-PAGE)
Gene :
IL-1B / IL-1 Beta
StandardGeneSymbol :
IL1B
gene family :
IL-1
Synonyms :
IL1B, IL-1B, IL-1 beta, IL1-BETA, Preinterleukin 1 beta, Pro-interleukin-1-beta, Catabolin, IL-1, IL1F2, Interleukin 1, beta, Interleukin-1 beta
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.