This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
protein
product name :
Human CCL16 / LEC Protein (Recombinant) - LS-G27271
catalog :
LS-G27271
product information
ProteinId :
27271
CatalogNumber :
LS-G27271
Product Name :
Human CCL16 / LEC Protein (Recombinant) - LS-G27271
Description :
Human HCC-4, also named NCC-4and Chemokine (C-C motif) ligand 16 (CCL16) is a small cytokine belonging to the CC chemokine family that is known under several pseudonyms, including Liver-expressed chemokine (LEC) and Monotactin-1 (MTN-1). It can signal through the CCR8 and CCR1 receptors, and it is chemotactic towards monocytes and lymphocytes but not neutrophils. HCC-4 is expressed weakly by some lymphocytes, including NK cells, T cells, and some T cell clones. The expression of HCC-4 in monocytes is greatly up-regulated in the presence of IL-10. HCC-4 induces a calcium flux in thp-1 cells that are desensitized prior to the expression of RANTES. Recombinant human HCC-4/CCL16 produced in CHO cells is a single non-glycosylated polypeptide chain containing 97 amino acids. A fully biologically active molecule, rhHCC-4/CCL16has a molecular mass of 12 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
PresentationDesc :
Lyophilized from PBS
ProteinType :
Recombinant
ProteinSpecies :
Human
ProteinSourceSpecies :
Hamster-Chinese
RecommendedStorage :
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.
Purification :
Greater than 98% by SDS-PAGE
PredictedMolecularWeight :
12 kDa (SDS-PAGE)
Gene :
CCL16 / LEC
StandardGeneSymbol :
CCL16
Subfamily :
Intercrine beta
gene family :
Intercrine
Synonyms :
CCL16, Cc chemokine lcc-1, CKb12, Chemokine hcc-4, Chemokine LEC, Chemokine lmc, ILINCK, Liver CC chemokine-1, Monotactin-1, NCC-4, LCC-1, LEC, Small-inducible cytokine A16, Liver-expressed chemokine, LMC, New CC chemokine 4, C-C motif chemokine 16, Chemokine CC-4, Chemokine ncc-4, HCC-4, IL-10-inducible chemokine, Mtn-1, NCC4, SCYA16, SCYL4
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.