protein

Human CCL14 Protein (Recombinant) - LS-G27256

LS-G27256

LS-G27256

Human CCL14 Protein (Recombinant) - LS-G27256

HCC-1/CCL14 is a member of the chemokine family, which are small chemotactic proteins that regulate cell migration under inflammatory and steady state conditions. HCC-1 is expressed in epithelial and decidual cells and is unique among chemokines due to its high abundance in normal human plasma. HCC-1 can bind to chemokine receptors CCR1 and CCR5, however full length HCC-1 is a weak agonist of CCR1 and only becomes potent after removal of its eight N-terminal residues. Chemokine decoy receptor D6 can bind HCC-1 and promote its degradation as a means to regulate its level in vivo. Functionally HCC-1 promotes trophoblast migration by regulating extracellular matrix components as well as specific adhesion molecules.Recombinant human Hemofiltrate CC Chemokine-1 (72 a.a.) (HCC-1)/CCL14 (rhHCC-1) produced in E. coli is a single non-glycosylated polypeptide chain containing 72 amino acids. A fully biologically active molecule, rhHCC-1 has a molecular mass of 8.4kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.

Lyophilized from PBS

Recombinant

Human

E. coli

Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 2 weeks or at -20°c for up to 3 months.

Reconstitute in ddH2O at 100 µg/ml

Greater than 95% by SDS-PAGE

8.4 kDa (SDS-PAGE)

CCL14

CCL14

Intercrine beta

Intercrine

CCL14, CC-3, C-C motif chemokine 14, Chemokine cc3, Chemokine CC-1/CC-3, Chemokine cc1, Chemokine CC-3, HCC-1(1-74), Hcc3, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, Small-inducible cytokine A14, SY14, CC-1, CKB1, HCC1, Hemofiltrate CC chemokine 1, NCC2, New CC chemokine 2

Worldwide