This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
protein
product name :
Human SERPINA12 / Vaspin Protein (Recombinant) - LS-G27250
catalog :
LS-G27250
product information
ProteinId :
27250
CatalogNumber :
LS-G27250
Product Name :
Human SERPINA12 / Vaspin Protein (Recombinant) - LS-G27250
Description :
Vaspin is a cytokine originally identified in visceral adipose tissue of Otsuka Long-Evans Tokushima fatty rats, and the name 'Vaspin' is short for visceral adipose tissue-derived serine protease inhibitor. Besides the visceral adipose, Vaspin is also expressed in the skin, hypothalamus, pancreatic islets and stomach, and is shown to exert an anti-inflammatory role by inhibiting several proinflammatory adipokines such as leptin, resistin, and Tumor Necrosis Factor-Alpha. Vaspin also stimulates adiponectin expression and improves insulin sensitivity in mice. Vaspin expression has been shown to decrease with worsening of diabetes and body weight loss. Accordingly, administration of recombinant human Vaspin improved glucose tolerance in diet regulated mice suggesting it as a potential target for obese-related diseases.
PresentationDesc :
Lyophilized from PBS
ProteinType :
Recombinant
ProteinSpecies :
Human
ProteinSourceSpecies :
E. coli
RecommendedStorage :
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 2 weeks or at -20°c for up to 3 months.
Purification :
Greater than 95% by non-reducing SDS-PAGE and HPLC
PredictedMolecularWeight :
45.1 kDa (SDS-PAGE)
Gene :
SERPINA12 / Vaspin
StandardGeneSymbol :
SERPINA12
Synonyms :
SERPINA12, Serpin A12, OL-64, Vaspin
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.