This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
protein
product name :
Human EGFR Protein (Recombinant His, C-Terminal) - LS-G27245
catalog :
LS-G27245
product information
ProteinId :
27245
CatalogNumber :
LS-G27245
Product Name :
Human EGFR Protein (Recombinant His, C-Terminal) - LS-G27245
Description :
Epidermal Growth Factor Receptor (EGFR) belongs to a family of tyrosine kinase receptors including Human EGF Receptors (HER) 2, 3, and 4 which all play important roles in cell growth and differentiation. Their primary ligands are EGF, Heparin-Binding EGF and Transforming Growth Factor Alpha. Upon ligand binding, EGFR undergoes asymmetric dimerization, composed of an 'activator' and a 'receiver'. EGFR and its family members are disregulated in numerous cancers. In particular, EGFR is overexpressed in many epithelial solid tumors. Evidence suggests EGFR is an excellent target for pharmacologic intervention in Non Small Cell Lung Cancer (NSCLC) due to its high level of expression and prominent role in tumor growth and metastasis.
PresentationDesc :
Lyophilized from PBS
ProteinTag :
His, C-Terminal
ProteinType :
Recombinant
ProteinSpecies :
Human
ProteinSourceSpecies :
Spodoptera frugiperda
RecommendedStorage :
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 2 weeks or at -20°c for up to 3 months.
ReconstitutionInstructions :
Reconstitute in ddH2O at 100 µg/ml
Purification :
Greater than 95% by non-reducing SDS-PAGE and HPLC
PredictedMolecularWeight :
80 kDa (SDS-PAGE)
Gene :
EGFR
StandardGeneSymbol :
EGFR
Subfamily :
EGF Receptor
gene family :
Protein Kinase
Synonyms :
EGFR, EGF Receptor, ERBB, ERBB1, MENA, PIG61, Proto-oncogene c-ErbB-1, V-erb-b homolog, EGF-R, HER1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.