This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
protein
product name :
Human IL18BP Protein (Recombinant) - LS-G27228
catalog :
LS-G27228
product information
ProteinId :
27228
CatalogNumber :
LS-G27228
Product Name :
Human IL18BP Protein (Recombinant) - LS-G27228
Description :
Interleukin-18 binding protein, also known as IL-18BP and tadekinig-alfa, is a secreted glycoprotein that contains an Ig-like C2-type domain. It is expressed in heart, lung, placenta and spleen. IL-18BP functions as an inhibitor of the proinflammatory cytokine IL-18. It binds to IL-18, prevents the binding of IL-18 to its receptor, and thus blocks IL-18-induced IFN-gamma production. The complete Ig domain has been shown to mediate the binding and neutralizing properties. IFN-gamma is able to upregulate the expression of IL-18BP, indicating that IL-18 activity is regulated by a feedback mechanism through IL-18BP.
PresentationDesc :
Lyophilized from PBS
ProteinType :
Recombinant
ProteinSpecies :
Human
ProteinSourceSpecies :
Hamster-Chinese
RecommendedStorage :
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.
Purification :
Greater than 95% by SDS-PAGE and HPLC
PredictedMolecularWeight :
42-44 kDa (SDS-PAGE)
Gene :
IL18BP
StandardGeneSymbol :
IL18BP
gene family :
Interleukin
Synonyms :
IL18BP, IL18BPa, Interleukin-18-binding protein, Interleukin 18 binding protein, Tadekinig-alfa, IL-18BP
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.