This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
protein
product name :
Mouse IL-1B / IL-1 Beta Protein (Recombinant) - LS-G27072
catalog :
LS-G27072
product information
ProteinId :
27072
CatalogNumber :
LS-G27072
Product Name :
Mouse IL-1B / IL-1 Beta Protein (Recombinant) - LS-G27072
Description :
Interleukin-1 (IL-1) is a family of cytokines that play a central role in the regulation of immune and inflammatory responses to infections or sterile insults. IL-1a and IL-1Beta are the first two members discovered in this family, which are the products of distinct genes recognizing the same cell surface receptors. IL-1a and IL-1Beta are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. The proteins are synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17.5 kDa. The specific protease responsible for the processing of IL-1Beta is interleukin 1Beta-converting enzyme (ICE)/caspase-1. Mature human and mouse IL-1Beta share approximately 75% amino acid sequence identity where human IL-1Beta has been found to be active on murine cell lines. GenScript Interleukin (IL)-1Beta, murine, produced in CHO cells, is a non-glycosylated polypeptide chain containing 152 amino acids and having a molecular mass of 17,400 Da.
PresentationDesc :
Lyophilized from PBS
ProteinType :
Recombinant
ProteinSpecies :
Mouse
ProteinSourceSpecies :
Hamster-Chinese
RecommendedStorage :
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.
Purification :
Greater than 95% by SDS-PAGE and HPLC
PredictedMolecularWeight :
17.4 kDa (SDS-PAGE)
Gene :
IL-1B / IL-1 Beta
StandardGeneSymbol :
IL1B
gene family :
IL-1
Synonyms :
IL1B, IL-1B, IL-1 beta, IL1-BETA, Preinterleukin 1 beta, Pro-interleukin-1-beta, Catabolin, IL-1, IL1F2, Interleukin 1, beta, Interleukin-1 beta
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.