product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
BBC3 / PUMA Antibody (aa119-154) LS-C98860
catalog :
LS-C98860
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Diaz Flores E, Comeaux E, Kim K, Melnik E, Beckman K, Davis K, et al. Bcl-2 Is a Therapeutic Target for Hypodiploid B-Lineage Acute Lymphoblastic Leukemia. Cancer Res. 2019;79:2339-2351 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-C98860 image 1
Western blot of anti-Puma BH3 domain antibody in HL-60 cell lysate. Puma BH3 domain (arrow) was detected using purified antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
image 2 :
LifeSpan Biosciences LS-C98860 image 2
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with Puma BH3 Domain antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
image 3 :
LifeSpan Biosciences LS-C98860 image 3
Confocal immunofluorescence of Puma BH3 Domain Antibody with HeLa cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
product information
AntibodyID :
100432
AntibodyName :
LS-C98860
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
BBC3 / PUMA Antibody (aa119-154) LS-C98860
Specificity :
This Puma BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-154 amino acids from human Puma BH3 Domain.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa119-154
PresentationDesc :
PBS, 0.09% Sodium Azide
PurificationDesc :
Ammonium sulfate precipitation
RecommendedStorageDesc :
Maintain refrigerated at 2°C to 8°C for up to 6 months. For long term storage store at -20°C.
Gene :
BBC3 / PUMA
BlockingPeptide :
LS-E2249
StandardGeneSymbol :
BBC3
gene family :
Apoptosis
Reactivity :
Mouse, Human
Usage :
Flo (1:10 - 1:50), IF (1:10 - 1:50), IHC, IHC-P (1:10 - 1:50), WB (1:1000)
ShortWebDescription :
PUMA antibody LS-C98860 is an unconjugated rabbit polyclonal antibody to PUMA (BBC3) (aa119-154) from human. It is reactive with human and mouse. Validated for Flow, IF, IHC and WB. Cited in 1 publication.
Synonyms :
BBC3, Bcl-2-binding component 3, BCL2 binding component 3, JFY-1, JFY1, PUMA, PUMA alpha
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.