This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
PAPPA / PAPP-A Antibody (clone 1_24) LS-C9690
catalog :
LS-C9690
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1_24
reactivity :
human
application :
western blot, ELISA, immunohistochemistry
product information
AntibodyID :
10431
AntibodyName :
LS-C9690
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
PAPPA / PAPP-A Antibody (clone 1_24) LS-C9690
Specificity :
Specific for native human PAPP-A. Heat and SDS denatured PAPP-A is also recognized, but not acid-treated PAPP-A. The epitope is different from those of clones 6F172 and 6F174 and is located on the PAPP-A subunit of the heterotetramer. In sandwich ELISA the optimal combination was clone 6F174 as coating and biotinylated clone 6F173 as detection. This product detects only unreduced PAPP-A in Western Blot. It gives the strongest signal in Immunohistochemistry compared to clone 6F172 and clone 6F174.
ClonalityDesc :
Monoclonal
CloneName :
1_24
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.2, 15 mM Sodium Azide
ImmunogenType :
Purified protein
ImmunogenDesc :
Purified human PAPP-A.
PurificationDesc :
Protein A/G purified
RecommendedStorageDesc :
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
IsotypeName :
IgG1,k
Gene :
PAPPA / PAPP-A
StandardGeneSymbol :
PAPPA
gene family :
Protease
Subfamily :
Metallopeptidase M43
Reactivity :
Human
Usage :
ELISA (1:8000), IHC, WB
ShortWebDescription :
PAPP-A antibody LS-C9690 is an unconjugated mouse monoclonal antibody to human PAPP-A (PAPPA). Validated for ELISA, IHC and WB.
UsageText :
Suitable for use in ELISA, Western Blot, and Immunohistochemistry. ELISA: 1:8000. In sandwich ELISA the optimal combination was clone 6F174 as coating and biotinylated clone 6F173 as detection. Western Blot: Detects only unreduced PAPP-A. Immunohistochemistry: Gives the strongest signal compared to clone 6F172 and clone 6F174.
Synonyms :
PAPPA, DIPLA1, IGF-dependent IGFBP-4 protease, PAPPA1, PAPA, PAPP-A, Pappalysin-1, ASBABP2, IGFBP-4ase
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.