product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
Monocytes, Macrophages Antibody (clone MOMA-2, Biotin) LS-C96374
catalog :
LS-C96374
clonality :
monoclonal
host :
rat
conjugate :
biotin
clone name :
MOMA-2
application :
immunohistochemistry, immunohistochemistry - frozen section
more info or order :
LifeSpan Biosciences product webpage
citations: 2
Reference
Ibrahim M, Barnes J, Osorio E, Anstead G, Jimenez F, Osterholzer J, et al. Deficiency of lymph node-resident dendritic cells (DCs) and dysregulation of DC chemoattractants in a malnourished mouse model of Leishmania donovani infection. Infect Immun. 2014;82:3098-112 pubmed publisher
Ibrahim M, Barnes J, Anstead G, Jimenez F, Travi B, Peniche A, et al. The malnutrition-related increase in early visceralization of Leishmania donovani is associated with a reduced number of lymph node phagocytes and altered conduit system flow. PLoS Negl Trop Dis. 2013;7:e2329 pubmed publisher
product information
AntibodyID :
97861
AntibodyName :
LS-C96374
Host Species :
Rat
Product Name :
Monocytes, Macrophages Antibody (clone MOMA-2, Biotin) LS-C96374
Specificity :
The antigen is a (glyco-)protein of 140kDa m.w. which is located within the cytoplasm and on the cell surface. The epitope has not been further characterized. Antigen distribution: Isolated cells: In the cytospin preparation of thioglycollate stimulated peritoneal exudate cells MOMA-2 detects an antigen as distinct cytoplasmic spots. MOMA-2 detects monocytes of the peripheral blood and a subpopulation of bone marrow cells Tissue sections MOMA-2 detects typical tissue macrophages as does the anti F4/80-specific clone BM8 (pan macrophage marker). However, different staining patterns are visible as shown below. The most predominant difference can be observed in T-cell areas and follicles of peripheral lymphoid organs where the anti F4/80 clone BM8 is negative. Specificity: Mouse: monocytes and macrophages. Other species: not tested.
ClonalityDesc :
Monoclonal
CloneName :
MOMA-2
AntibodyModification :
Biotin
PresentationDesc :
Lyophilized from PBS pH 7.2, 5mg/ml BSA, 0.1% sodium azide
ImmunogenDesc :
Mouse Lymph node stroma
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C.
ResuspensionLiquidDesc :
Reconstitute with 0.5ml distilled H2O.
Gene :
Monocytes, Macrophages
Reactivity :
Mouse
Usage :
IHC, IHC-Fr (1:3000)
ShortWebDescription :
Monocytes, Macrophages antibody LS-C96374 is a biotin-conjugated rat monoclonal antibody to mouse Monocytes, Macrophages. Validated for IHC. Cited in 2 publications.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.