This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
DEF / Defensin Antibody (clone Def-3) LS-C96234
catalog :
LS-C96234
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Def-3
application :
immunohistochemistry, immunohistochemistry - paraffin section
product information
AntibodyID :
97721
AntibodyName :
LS-C96234
Host Species :
Mouse
Product Name :
DEF / Defensin Antibody (clone Def-3) LS-C96234
Specificity :
Several defensins are recognized, the epitope has not been further characterized. Biological functions: Various functions have been described for defensins. They are antibacterial, antifungal, chemotactic for monocytes, inhibitory for ACTH-induced corticosteroid synthesis and cytotoxic for cells. Defensins are inhibited by glucosaminoglycans (self protection for cells) and high concentrations of Calpha 2+ ions. Biochemistry: Defensins are a group of cyclic peptides containing 29-35 amino acids (MW < 3500) which tend to form aggregates. The molecules are protease resistant. The defensin content of azurophilic granules in neutrophils is approximately 30% of the total protein. Specificity: Human: Defensin 1-3 (HNP-1 to HNP-3) in human neutrophils. Synthetic defensin-1 and -2 (Bachem, Bubendorf CH) stain also positively. Not tested with Defensin-4. A side reaction to elastin has been observed in humans. Other: not tested. Defensins have been described in rabbits (NP-1 to NP-5, NP3a = Corticostatin), and in mice (cryptodin).
ClonalityDesc :
Monoclonal
CloneName :
Def-3
AntibodyModification :
Unconjugated
PresentationDesc :
Lyophilized from PBS, pH 7.2, 5 mg/ml BSA, 0.09% Sodium Azide
ImmunogenDesc :
Native defensins
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C.
ResuspensionLiquidDesc :
Reconstitute with 0.5ml distilled H2O.
Gene :
DEF / Defensin
Reactivity :
Human
Usage :
IHC, IHC-P (1:1000)
ShortWebDescription :
Defensin antibody LS-C96234 is an unconjugated mouse monoclonal antibody to human Defensin (DEF). Validated for IHC.
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.