This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
S100A8 / MRP8 Antibody (clone S13-67) LS-C96232
catalog :
LS-C96232
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S13-67

The same clone is also sold as:
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
product information
AntibodyID :
97719
AntibodyName :
LS-C96232
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
S100A8 / MRP8 Antibody (clone S13-67) LS-C96232
Specificity :
The antigen is MRP8, the epitope is suspected in the N- or C- terminal domain. Antigen distribution: Isolated cells: The antigen is found in granulocytes and monocytes. It is absent from other blood cells. In cultured monocytes, maximum MRP8 levels occur after 3 - 4 days. Tissue sections: MRP8 is found in a distinct subpopulation of inflammatory perivascular infiltrates of the myelo-monocytic lineage. Macrophages increasingly synthesise MRP8 during the late stages of inflammation. A low MRP8 (and high MRP14) expression by macrophages was also reported in granulomatous diseases such as tuberculosis and sarcoidis. In non-granulomatous chronic inflammatory diseases such as chronic rheumatoid arthritis, MRP8 and MRP14 positive cells consist of different subpopulations. During early inflammation endothelial cells are also positive with MRP8 / MRP14. Specificity: Human: granulocytes, stimulated monocytes and macrophages. Other: rat; cow; pig (TNF-alpha/IL-1 alpha induced inflammation of the skin).
ClonalityDesc :
Monoclonal
CloneName :
S13-67
AntibodyModification :
Unconjugated
PresentationDesc :
Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.01% thimerosal
ImmunogenDesc :
Cultured human monocytes
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C.
ResuspensionLiquidDesc :
Reconstitute with 0.5ml distilled H2O.
Gene :
S100A8 / MRP8
StandardGeneSymbol :
S100A8
Reactivity :
Human
Usage :
ELISA, IHC, IHC-P
ShortWebDescription :
MRP8 antibody LS-C96232 is an unconjugated mouse monoclonal antibody to human MRP8 (S100A8). Validated for ELISA and IHC.
Synonyms :
S100A8, 60B8AG, CFAG, CAGA, Calgranulin A, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen, CGLA, L1Ag, NIF, p8, Protein S100-A8, MRP8, Urinary stone protein band A, CP-10, MA387, MRP-8
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.