This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CASP8 / Caspase 8 Antibody (N-Terminus) LS-C95930
catalog :
LS-C95930
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry
product information
AntibodyID :
97307
AntibodyName :
LS-C95930
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
CASP8 / Caspase 8 Antibody (N-Terminus) LS-C95930
Specificity :
Reacts with a 55 kD protein. Caspase 8 has an N-terminal domain with sequence homology to the death effector domain (DED) of FADD. Caspase 8 binds to DED of FADD. Caspase 8 is activated by association with Fas/FADD death-inducing signaling complex to release two active subunits, p18 and p10 into the cytosol, where they activate other Caspases amplifying the apoptotic signal. This antibody cross reacts with mouse, rat, monkey and cow.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
N-Terminus
PresentationDesc :
0.05% Sodium Azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant full-length human Caspase 8 protein.
PurificationDesc :
Ig fraction
RecommendedStorageDesc :
Store at 2°C to 8°C. Do not freeze.
Gene :
CASP8 / Caspase 8
StandardGeneSymbol :
CASP8
gene family :
Protease
Subfamily :
Cysteine C14
Reactivity :
Mouse, Bovine, Rat, Human, Monkey
Usage :
IHC
ShortWebDescription :
Caspase 8 antibody LS-C95930 is an unconjugated rabbit polyclonal antibody to Caspase 8 (CASP8) (N-Terminus) from human. It is reactive with human, mouse, rat and other species. Validated for IHC.
Synonyms :
CASP8, ALPS2B, Apoptotic protease Mch-5, Apoptotic cysteine protease, Casp-8, Caspase-8, CAP4, Caspase 8, MACH, MCH5, MORT1-associated ced-3 homolog, ICE-like apoptotic protease 5, Pro Caspase 8, FADD-like ICE, FLICE, MACH-alpha-1/2/3 protein, MACH-beta-1/2/3/4 protein
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.