This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CASP1 / Caspase 1 Antibody LS-C95899
catalog :
LS-C95899
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry
product information
AntibodyID :
97276
AntibodyName :
LS-C95899
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
CASP1 / Caspase 1 Antibody LS-C95899
Specificity :
Reacts with a 45 kD protein, Caspase 1 and is expressed as a proenzyme in many tissues. Active Caspase 1 is a tetramer of two subunits p10 and p20 in 2:2 ratio. Overexpression of Caspase 1 can induce apoptosis in fibroblast, which can be inhibited by Overexpression of Crm A, a protein from pox virus. This antibody cross reacts with human, mouse and rat.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
0.05% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A synthetic peptide from the second quarter of human Caspase 1 protein.
PurificationDesc :
Ig fraction
RecommendedStorageDesc :
Store at 2°C to 8°C. Do not freeze.
Gene :
CASP1 / Caspase 1
StandardGeneSymbol :
CASP1
gene family :
Protease
Subfamily :
Cysteine C14
Reactivity :
Mouse, Rat, Human
Usage :
IHC (1:25 - 1:50), WB
ShortWebDescription :
Caspase 1 antibody LS-C95899 is an unconjugated rabbit polyclonal antibody to Caspase 1 (CASP1) from human. It is reactive with human, mouse and rat. Validated for IHC and WB.
UsageText :
IHC-P requires HIER treatment with 10 mM sodium citrate buffer, pH 6.0.
Synonyms :
CASP1, Caspase-1, CASP-1, CASP1 nirs variant 1, Caspase 1, ICE, ICE-like protease, IL-1 beta-converting enzyme, IL-1BC, IL1BC, IL1BCE, p45, IL1B-convertase, Interleukin-1 beta convertase
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.