This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
BCL10 / BCL-10 Antibody (aa122-168, clone 151) LS-C95617
catalog :
LS-C95617
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
151

The same clone is also sold as:
reactivity :
human
product information
AntibodyID :
96994
AntibodyName :
LS-C95617
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
BCL10 / BCL-10 Antibody (aa122-168, clone 151) LS-C95617
Specificity :
Monoclonal Anti-Bcl-10 reacts specifically with human Bcl-10. The epitope recognized by the antibody resides within amino acids 122-168 of human Bcl-10 molecule. Bcl-10, also designated as CIPER, mE10, cE10, CARMEN, and CLAP, is an N-terminal CARD (Caspase Recruitment Domain) containing protein. It is a cellular homologue of the equine herpesvirus-2 protein E-10 (vCLAP). Bcl-10 was implicated in the regulation of apoptosis by interacting with caspase 9, enhancing procaspase 9 processing, and triggering its activation when overexpressed in the cell. Bcl-10 cellular overexpression induces JNK, p38, and NF-kB activation. Deregulation of Bcl-10 expression is also demonstrated to be involved in cellular oncogenesis.
ClonalityDesc :
Monoclonal
CloneName :
151
AntibodyModification :
Unconjugated
AntigenModification :
aa122-168
PresentationDesc :
0.05% Sodium Azide
ImmunogenDesc :
Human recombinant Bcl-10.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C. Do not freeze.
IsotypeName :
IgG1
Gene :
BCL10 / BCL-10
StandardGeneSymbol :
BCL10
gene family :
Apoptosis
Reactivity :
Human
ShortWebDescription :
BCL-10 antibody LS-C95617 is an unconjugated mouse monoclonal antibody to human BCL-10 (BCL10) (aa122-168).
Synonyms :
BCL10, Bcl-10, B-cell CLL/lymphoma 10, B-cell lymphoma/leukemia 10, CARMEN, CARD-like apoptotic protein, CCARMEN, C-E10, CIPER, Cellular-E10, HCLAP, Cellular homolog of vCARMEN, CLAP, ME10
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.