This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
MLH1 Antibody (clone G168-15) LS-C95607
catalog :
LS-C95607
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
G168-15

The same clone is also sold as:
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
product information
AntibodyID :
96984
AntibodyName :
LS-C95607
Host Species :
Mouse
Product Name :
MLH1 Antibody (clone G168-15) LS-C95607
Specificity :
The G168-15 antibody recognizes the human and mouse MLH1 (80-85kDa. The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC). MSH-2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process. It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair. cross reacts with human, hamster and rat
ClonalityDesc :
Monoclonal
CloneName :
G168-15
AntibodyModification :
Unconjugated
PresentationDesc :
Supplied as a liquid containing sodium azide as a preservative
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Full length recombinant MLH.
RecommendedStorageDesc :
Store at 2°C to 8°C. Do not freeze.
IsotypeName :
IgG1
Gene :
MLH1
StandardGeneSymbol :
MLH1
Reactivity :
Rat, Hamster, Human
Usage :
IHC, IHC-P
ShortWebDescription :
MLH1 antibody LS-C95607 is an unconjugated mouse monoclonal antibody to MLH1 from human, rat and hamster. Validated for IHC.
Synonyms :
MLH1, COCA2, FCC2, HMLH1, HNPCC, HNPCC2, MutL protein homolog 1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.