This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
MSH6 Antibody (clone 44) LS-C95606
catalog :
LS-C95606
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
44

The same clone is also sold as:
reactivity :
human
application :
western blot, immunoprecipitation
product information
AntibodyID :
96983
AntibodyName :
LS-C95606
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
MSH6 Antibody (clone 44) LS-C95606
Specificity :
MSH6 is a heterodimer of MSH2 and binds to DNA containing G/T mismatches. The MSH2-MSH6 complex recognizes a single-based mispair insertion/deletion loop. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related human carcinogenesis. Studies have shown the mutations of MLH-1, MSH2 and MSH6 genes contribute to the development of sporadic colorectal carcinoma. The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. cross reacts with mouse, rat and dog.
ClonalityDesc :
Monoclonal
CloneName :
44
AntibodyModification :
Unconjugated
PresentationDesc :
0.05% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic human MSH6 peptide.
PurificationDesc :
Purified
RecommendedStorageDesc :
Store at 2°C to 8°C. Do not freeze.
IsotypeName :
IgG1
Gene :
MSH6
StandardGeneSymbol :
MSH6
Reactivity :
Mouse, Dog, Rat, Human
Usage :
IP, WB (1:100 - 1:500)
ShortWebDescription :
MSH6 antibody LS-C95606 is an unconjugated mouse monoclonal antibody to MSH6 from human. It is reactive with human, mouse, rat and other species. Validated for IP and WB.
Synonyms :
MSH6, GTBP, HSAP, GTMBP, MutS (E. coli) homolog 6, HMSH6, Sperm-associated protein, p160, G/T mismatch-binding protein, HNPCC5, MutS homolog 6 (E. coli), MutS-alpha 160 kDa subunit
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.