TRPV4 Antibody (aa100-150) LS-C94498 | LifeSpan Biosciences LS-C94498 product information

product summary

company name :

LifeSpan Biosciences

product type :

antibody

product name :

TRPV4 Antibody (aa100-150) LS-C94498

catalog :

LS-C94498

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section

more info or order :

LifeSpan Biosciences product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; rat	Arredondo Zamarripa D, Noguez Imm R, Bautista Cortés A, Vázquez Ruíz O, Bernardini M, Fiorio Pla A, et al. Dual contribution of TRPV4 antagonism in the regulatory effect of vasoinhibins on blood-retinal barrier permeability: diabetic milieu makes a difference. Sci Rep. 2017;7:13094 pubmed publisher
immunohistochemistry; mouse	Gu Y, Jukkola P, Wang Q, Esparza T, Zhao Y, Brody D, et al. Polarity of varicosity initiation in central neuron mechanosensation. J Cell Biol. 2017;216:2179-2199 pubmed publisher
immunohistochemistry; mouse; 1:1000; loading ...; fig 1e immunocytochemistry; human; 1:1000; fig 1c immunohistochemistry; human; 1:1000; loading ...; fig 1f western blot; human; fig 1b	Ryskamp D, Frye A, Phuong T, Yarishkin O, Jo A, Xu Y, et al. TRPV4 regulates calcium homeostasis, cytoskeletal remodeling, conventional outflow and intraocular pressure in the mammalian eye. Sci Rep. 2016;6:30583 pubmed publisher
	Gao F, Yang Z, JACOBY R, Wu S, Pang J. The expression and function of TRPV4 channels in primate retinal ganglion cells and bipolar cells. Cell Death Dis. 2019;10:364 pubmed publisher
	Yarishkin O, Phuong T, Lakk M, Krizaj D. TRPV4 Does Not Regulate the Distal Retinal Light Response. Adv Exp Med Biol. 2018;1074:553-560 pubmed publisher
	Zalis M, Johansson S, Englund Johansson U. Immunocytochemical Profiling of Cultured Mouse Primary Retinal Cells. J Histochem Cytochem. 2017;65:223-239 pubmed publisher

product information

AntibodyID :

95719

AntibodyName :

LS-C94498

TargetSpecies :

Mouse

Host Species :

Rabbit

Product Name :

TRPV4 Antibody (aa100-150) LS-C94498

Specificity :

Specific for TRPV4.

ClonalityDesc :

Polyclonal

AntibodyModification :

Unconjugated

AntigenModification :

aa100-150

PresentationDesc :

Lyophilized

ImmunogenType :

Synthetic peptide

ImmunogenDesc :

Synthetic peptide from 1t cytoplasmic domain of mouse TRPV4 conjugated to an immunogenic carrier protein.

PurificationDesc :

Antiserum

RecommendedStorageDesc :

Maintain lyophilized and reconstituted antibodies at -20°C for long term storage and at 2°C to 8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze/thaw cycles.

ResuspensionLiquidDesc :

Reconstitute with 100 µl sterile water.

Gene :

TRPV4

StandardGeneSymbol :

TRPV4

gene family :

Ion Channel

Subfamily :

Calcium channel - TRP

Reactivity :

Mouse, Rat

Usage :

IF, IHC, IHC-Fr, WB

ShortWebDescription :

TRPV4 antibody LS-C94498 is an unconjugated rabbit polyclonal antibody to TRPV4 (aa100-150) from mouse. It is reactive with mouse and rat. Validated for IF, IHC and WB. Cited in 7 publications.

UsageText :

IHC: Antigen retrieval is essential for use on paraffin sections.

Synonyms :

TRPV4, CMT2C, HMSN2C, OTRPC4, SSQTL1, VR-OAC, VRL-2, Osm-9-like TRP channel 4, SPSMA, TRP12, VRL2, VROAC, SMAL

SalesRegion :

Worldwide

more info or order :

LifeSpan Biosciences product webpage

company information

LifeSpan Biosciences

2401 Fourth Avenue, Suite 900
Seattle, WA 98121

CustomerSupport@lsbio.com

https://www.lsbio.com

1-206-464-1554

headquarters: USA

Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.