This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CCL4 / MIP-1 Beta Antibody LS-C8611
catalog :
LS-C8611
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, neutralization
product information
AntibodyID :
9352
AntibodyName :
LS-C8611
TargetSpecies :
Human
Host Species :
Goat
Product Name :
CCL4 / MIP-1 Beta Antibody LS-C8611
Specificity :
Recognizes Macrophage Inflammatory Protein 1 beta (MIP1 beta). based on ELISA and Western Blot data, <10% cross-reactivity with mouse MIP-1b, human MIP-1b, human MCP-2 and <5% cross-reactivity with mouse MIP-1b. <1% cross-reactivity with other chemokines tested.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.2, 40% Glycerol
ImmunogenDesc :
Sf 21-derived Recombinant, human Macrophage Inflammatory Protein 1 beta (MIP1 beta, CCL4).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG
Gene :
CCL4 / MIP-1 Beta
StandardGeneSymbol :
CCL4
gene family :
Intercrine
Subfamily :
Intercrine beta
Reactivity :
Mouse, Human
Usage :
ELISA (0.5 - 1 µg/ml), IHC (0.5 - 5 µg/ml), Neut (0.3 - 1.5 µg/ml), WB (0.1 - 0.2 µg/ml)
ShortWebDescription :
MIP-1 Beta antibody LS-C8611 is an unconjugated goat polyclonal antibody to MIP-1 Beta (CCL4) from human. It is reactive with human and mouse. Validated for ELISA, IHC, Neut and WB.
UsageText :
Suitable for use in neutralization of bioactivity, ELISA, Western Blot, and Immunohistochemistry. Neutralization: 0.3-1.5 ug/ml in the presence of 0.04 ug/ml of rhMIP-1b, using the BaF/3 hCCR5 transfected cell chemotaxis assay. In chemotaxis assays, this antibody will neutralize the biological activity of human MIP-1b and mouse MIP-1b at a 25-fold higher IgG concentration. Will not neutralize the biological activity of mouse MIP1b. ELISA: 0.5-1 ug/ml with the appropriate secondary reagents to detect human MIP-1b. The detection limit is ~0.3 ng/well. Western Blot: 0.1-0.2 ug/ml. The detection limit is 1.5-3.0 ng/lane, under non-reducing and reducing conditions. Immunohistochemistry: 0.5-5 ug/ml in cultured cells or tissue. sections.
Synonyms :
CCL4, ACT2, Act-2, AT744.1, C-C motif chemokine 4, Chemokine (C-C motif) ligand 4, CC chemokine ligand 4, HC21, LAG1, MIP1B, MIP1B1, LAG-1, SCYA2, Secreted protein G-26, SIS-gamma, MIP-1-beta, MIP-1-beta(1-69), Small-inducible cytokine A4, T-cell activation protein 2, G-26, Lymphocyte-activation gene 1, PAT 744, Protein H400, SCYA4
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.
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