This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
ESR2 / ER Beta Antibody (aa1-153) LS-C83437
catalog :
LS-C83437
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot
product information
AntibodyID :
84276
AntibodyName :
LS-C83437
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
ESR2 / ER Beta Antibody (aa1-153) LS-C83437
Specificity :
Recognizes human ER-beta, a novel receptor (approx. 52 kD) recently isolated from testis. The size and structure of ER-beta are very similar to ER-alpha with the ligand and DNA binding domains being highly conserved. The N-terminus of each receptor, which serves as their transactivation domain, are significantly different. Like ER-alpha, ER-beta binds to estrogen with a high affinity and regulates estrogen-specific gene activation through direct interaction with estrogen response elements.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa1-153
PresentationDesc :
PBS, pH 7.4
ImmunogenType :
Fusion protein
ImmunogenDesc :
6-His fusion protein containing the region encoding aa 1-153 of human estrogen receptor-a (ER-a) expressed in E. coli.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at -70°C, avoid freeze/thaw cycles.
IsotypeName :
IgG2b
Gene :
ESR2 / ER Beta
StandardGeneSymbol :
ESR2
gene family :
NHR
Subfamily :
NR3 Steroid receptor
Reactivity :
Human
Usage :
WB (1 - 5 µg/ml)
ShortWebDescription :
ER Beta antibody LS-C83437 is an unconjugated mouse monoclonal antibody to human ER Beta (ESR2) (aa1-153). Validated for WB.
Synonyms :
ESR2, ESTRB, ER Beta, ERbeta, ER-BETA, ESR-BETA, ESRB, Estrogen receptor 2 (ER beta), NR3A2, Estrogen receptor beta, Estrogen receptor beta 4
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.