This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
BRCA1 Antibody (aa762-1315) LS-C83427
catalog :
LS-C83427
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunoprecipitation
product information
AntibodyID :
84266
AntibodyName :
LS-C83427
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
BRCA1 Antibody (aa762-1315) LS-C83427
Specificity :
Recognizes full-length BRCA1, a 220 kD nuclear phosphoprotein, and does not recognize the ~exon 11 splice variant. In a high proportion of breast and ovarian cancer cell lines, BRCA1 aberrantly mislocates to the cytoplasm. Its usefulness to monitor functional inactivation of BRCA1 in sporadic breast cancers is under active investigation.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa762-1315
PresentationDesc :
PBS, pH 7.4
ImmunogenType :
Fusion protein
ImmunogenDesc :
GST fusion protein expressed in E. coli corresponding to aa 762-1315 of full-length BRCA1.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
BRCA1
StandardGeneSymbol :
BRCA1
Reactivity :
Human
Usage :
IHC (1 - 10 µg/ml), IP (1 - 10 µg/ml), WB (1 - 10 µg/ml)
ShortWebDescription :
BRCA1 antibody LS-C83427 is an unconjugated mouse monoclonal antibody to human BRCA1 (aa762-1315). Validated for IHC, IP and WB.
Synonyms :
BRCA1, BROVCA1, BRCC1, Breast cancer 1, early onset, PPP1R53, PSCP, PNCA4, RING finger protein 53, RNF53, BRCAI, Breast cancer 1 early onset, IRIS
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.