This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
KLKB1 / Plasma Kallikrein Antibody (clone 13G11) LS-C83337
catalog :
LS-C83337
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
13G11

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA
product information
AntibodyID :
84176
AntibodyName :
LS-C83337
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
KLKB1 / Plasma Kallikrein Antibody (clone 13G11) LS-C83337
Specificity :
This antibody recognizes two variants of prekallikrein in human plasma, 88kDa and85kDa, and its activation products kallikrein, the complexes formed by kallikrein with itsendogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and antithrombin III, and 45kDaprekallikrein/kallikrein fragments. It also recognizes prekallikrein and its activation products inchimpanzee, rhesus, and baboon plasmas. The epitope for this antibody is located on theprekallikrein/kallikrein heavy chain and is involved in the interaction between prekallikrein andfactor XIIa. This antibody inhibits prekallikrein activation in human and rhesus plasmas by ~60-80% and 55%, respectively. This antibody does not cross-react with tissue kallikrein.
ClonalityDesc :
Monoclonal
CloneName :
13G11
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.4
ImmunogenDesc :
Purified human Kallikrien
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
KLKB1 / Plasma Kallikrein
StandardGeneSymbol :
KLKB1
gene family :
Protease
Subfamily :
Serine S1
Reactivity :
Human
Usage :
ELISA, WB
ShortWebDescription :
Plasma Kallikrein antibody LS-C83337 is an unconjugated mouse monoclonal antibody to human Plasma Kallikrein (KLKB1). Validated for ELISA and WB.
UsageText :
May be used in ELISA and Western blots to identify/quantitate prekallikrein and its activation products in plasmas of humans, chimpanzees, rhesus monkeys, and baboons. NOTE: Prekallikrein activation may occur with repeated freezing/thawing (3x or more) of plasma samples obtained from humans or other primates.
Synonyms :
KLKB1, Fletcher factor deficiency, Fletcher factor, Kininogenin, Plasma kallikrein, PKK deficiency, Plasma kallikrein heavy chain, PPK, Prekallikrein deficiency, Plasma kallikrein light chain, Plasma prekallikrein, Kallikrein 3
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.