product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IGF1 Antibody LS-C7504
catalog :
LS-C7504
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, neutralization, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; human
Somasundaram R, Zhang G, Fukunaga Kalabis M, Perego M, Krepler C, Xu X, et al. Tumor-associated B-cells induce tumor heterogeneity and therapy resistance. Nat Commun. 2017;8:607 pubmed publisher
product information
AntibodyID :
8245
AntibodyName :
LS-C7504
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IGF1 Antibody LS-C7504
Specificity :
Recognizes human IGF1. Cross-reactivity with IGF-II: ~40%. Species cross-reactivity: mouse, rat and possibly chicken. Occasional difficulty neutralizing rat IGF1 due to binding protein interference.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
PresentationDesc :
Supplied as a lyophilized powder from 0.1M Tris-glycine, pH 7.4, 0.15mM sodium chloride, 0.1mM EDTA. No preservative added.
ImmunogenType :
Purified protein
ImmunogenDesc :
Human insulin-like growth factor I (IGF1) purified from human plasma.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at -20°C prior to reconstitution. After reconstitution aliquot and freeze at-20°C. Avoid freeze-thaw cycles.
ResuspensionLiquidDesc :
Reconstitute with 200ul sterile ddH2O
IsotypeName :
IgG1,k
Gene :
IGF1
StandardGeneSymbol :
IGF1
gene family :
Hormone
Reactivity :
Mouse, Rat, Human
Usage :
IHC, IHC-P (10 µg/ml), IP, Neut (10 - 20 µg/ml), WB (0.5 - 2 µg/ml)
ShortWebDescription :
IGF1 antibody LS-C7504 is an unconjugated mouse monoclonal antibody to IGF1 from human. It is reactive with human, mouse and rat. Validated for IHC, IP, Neut and WB. Cited in 1 publication.
UsageText :
Suitable for use in Western Blot, Immunoprecipitation, Neutralization and Immunohistochemistry. Immunoprecipitation: 5 ug immunoprecipitated 100 ng IGF1. Neutralization: 10-20 ug/ml can inhibit the activity of 10 ng/ml of IGF1 as determined by testing with chicken embryo fibroblasts (CEF) using an ATP endpoint assay. Immunohistochemistry: 10 ug/ml. Reported to detect IFG1 in formalin-fixed, paraffin-embedded skin sections.
Synonyms :
IGF1, IGF-IA, IGF-IB, IGFI, IBP1, IGF-I, Insulin-like growth factor 1, Insulin-like growth factor I, Insulin-like growth factor IA, Insulin-like growth factor IB, Mechano growth factor, Somatomedin-C, IGF1A, MGF
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.