product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IL6R / IL6 Receptor Antibody (Extracellular Domain) LS-C70920
catalog :
LS-C70920
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; mouse
Wang X, Miller E, Goswami M, Zhang P, Ronning K, Karlen S, et al. Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130. J Neuroinflammation. 2017;14:121 pubmed publisher
product information
AntibodyID :
71546
AntibodyName :
LS-C70920
TargetSpecies :
Mouse
Host Species :
Rat
Product Name :
IL6R / IL6 Receptor Antibody (Extracellular Domain) LS-C70920
Specificity :
Recognizes mouse IL-6Ralpha. In direct ELISAs and Western Blots, this antibody does not cross-react with rhIL-6R.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
AntigenModification :
Extracellular Domain
PresentationDesc :
Lyophilized from PBS, pH 7.4, 5% Trehalose
ImmunogenDesc :
NS0-derived rmIL-6Ralpha extracellular domain (aa 20-357) P22272
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C.
ResuspensionLiquidDesc :
Reconstitute in 200 ul sterile PBS
IsotypeName :
IgG1
Gene :
IL6R / IL6 Receptor
StandardGeneSymbol :
IL6R
gene family :
Interleukin
Reactivity :
Mouse
Usage :
ELISA, WB
ShortWebDescription :
IL6 Receptor antibody LS-C70920 is an unconjugated rat monoclonal antibody to mouse IL6 Receptor (IL6R) (Extracellular Domain). Validated for ELISA and WB. Cited in 1 publication.
UsageText :
Western Blot: This antibody can be used at 1-2 ug/mL with the appropriate secondary reagents to detect mouse IL-6 R. Using a colorimetric detection system, the detection limit for rmIL-6 R is approximately 25 ng/lane under non-reducing and reducing conditions. Chemiluminescent detection will increase sensitivity by 5 to 50 fold. Direct ELISA: This antibody can be used at 0.5-1.0 ug/mL with the appropriate secondary reagents to detect mouse IL-6 R. The detection limit for rmIL-6 R is approximately 5 ng/well.
Synonyms :
IL6R, CD126, gp80, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6Q, IL-6 receptor subunit alpha, IL-6R 1, IL-6R-1, Interleukin 6 receptor, Membrane glycoprotein 80, CD126 antigen, IL6RA, IL6RQ
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.