product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
FZD4 / Frizzled 4 Antibody (Extracellular Domain) LS-C6904
catalog :
LS-C6904
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunocytochemistry, flow cytometry
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Ueno K, Hirata H, Majid S, Yamamura S, Shahryari V, Tabatabai Z, et al. Tumor suppressor microRNA-493 decreases cell motility and migration ability in human bladder cancer cells by downregulating RhoC and FZD4. Mol Cancer Ther. 2012;11:244-53 pubmed publisher
product information
AntibodyID :
7645
AntibodyName :
LS-C6904
TargetSpecies :
Mouse
Host Species :
Rat
Product Name :
FZD4 / Frizzled 4 Antibody (Extracellular Domain) LS-C6904
Specificity :
Recognizes mouse Frizzled-4. Shows no cross-reactivity with rmFrizzled-1, -2, 3, -6, -7 -8 or rhFrizzled-5. Species cross-reactivity: Human. Detects Frizzled-4 by Flow Cytometry and Immunohistochemistry on mouse differentiated embryoid bodies derived from the mouse embryonic cell line, D3. Also recognizes human Frizzled-4 by Flow Cytometry and Immunohistochemistry on HEK 293 cells.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
AntigenModification :
Extracellular Domain
PresentationDesc :
PBS, pH 7.4, 5% Trehalose
ImmunogenDesc :
NS0-derived rmFrizzled-4 extracellular domain.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG2a
Gene :
FZD4 / Frizzled 4
StandardGeneSymbol :
FZD4
gene family :
GPCR
Subfamily :
Frizzled
Reactivity :
Mouse, Human
Usage :
Flo (100 µg/ml), ICC (10 µg/ml), WB (1 - 2 µg/ml)
ShortWebDescription :
Frizzled 4 antibody LS-C6904 is an unconjugated rat monoclonal antibody to Frizzled 4 (FZD4) (Extracellular Domain) from mouse. It is reactive with human and mouse. Validated for Flow, ICC and WB. Cited in 1 publication.
UsageText :
Suitable for use in Flow Cytometry, Immunocytochemistry and Western Blot. Flow Cytometry: 100 ug/ml. Add 10 ul to 1-2.5x10^5 cells. Total reaction volume should not exceeding 200ul. Immunocytochemistry: 10 ug/ml in 4% paraformaldehyde-fixed cells. Western Blot:1-2 ug/ml. The detection limit is ~5 ng/lane under non-reducing and reducing conditions.
Synonyms :
FZD4, CD344, CD344 antigen, EVR1, Frizzled family receptor 4, Frizzled-4, Fz-4, Fz4, HFz4, Exudative vitreoretinopathy 1, FEVR, FZD4S, FzE4, Frizzled 4, Frizzled homolog 4, WNT receptor frizzled-4
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.