This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
FXN / Frataxin Antibody LS-C6889
catalog :
LS-C6889
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunocytochemistry
product information
AntibodyID :
7630
AntibodyName :
LS-C6889
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
FXN / Frataxin Antibody LS-C6889
Specificity :
Recognizes only isoforms of human Frataxin containing exon 4. On Western Blots of normal human muscle, heart, cerebellum, and spinal cord extracts, antibody recognizes a band migrating at ~18kD corresponding to processed human frataxin (Campuzano, 1997). Slight cross reactivity with myosin may be observed by Western Blot. Immunofluorescent labeling of HeLa cells with This antibody demonstrates that frataxin is predominantly localized in the mitochondria (Campuzano, 1997). Species cross-reactivity: mouse.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 40% Glycerol, No preservatives added
ImmunogenType :
Purified protein
ImmunogenDesc :
TrpE-Frataxin full length. Epitope: Maps to the first part of exon 4 of frataxin.
PurificationDesc :
Ascites
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1,k
Gene :
FXN / Frataxin
StandardGeneSymbol :
FXN
Reactivity :
Mouse, Human
Usage :
ELISA, IF (1:50 - 1:500), WB
ShortWebDescription :
Frataxin antibody LS-C6889 is an unconjugated mouse monoclonal antibody to Frataxin (FXN) from human. It is reactive with human and mouse. Validated for ELISA, IF and WB.
UsageText :
Suitable for use in Western Blot, Immunofluorescence and ELISA. Western Blot (Natural and recombinant protein): 1:2500. Immunofluorescence: 1:50-1:500. Fixation of cells in ice cold acetone or 4% paraformaldehyde is recommended. Due to subcellular localization of frataxin in the mitochondria, cells should be permeabilized in the presence of detergent prior to incubation with primary antibody. Positive control: Liver, heart or skeletal muscle.
Synonyms :
FXN, CyaY, Frataxin, mitochondrial, Friedreich ataxia protein, FARR, Friedreich ataxia, FA, FRDA, X25, Frataxin
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.