product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
EGFR Antibody (phospho-Tyr1173) LS-C6611
catalog :
LS-C6611
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human
application :
western blot, ELISA, immunoprecipitation
more info or order :
LifeSpan Biosciences product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • western blot; human
Aggerholm Pedersen N, Demuth C, Safwat A, Meldgaard P, Kassem M, Sandahl Sorensen B. Dasatinib and Doxorubicin Treatment of Sarcoma Initiating Cells: A Possible New Treatment Strategy. Stem Cells Int. 2016;2016:9601493 pubmed publisher
Demuth C, Andersen M, Jakobsen K, Madsen A, Sørensen B. Increased PD-L1 expression in erlotinib-resistant NSCLC cells with MET gene amplification is reversed upon MET-TKI treatment. Oncotarget. 2017;8:68221-68229 pubmed publisher
product information
AntibodyID :
7352
AntibodyName :
LS-C6611
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
EGFR Antibody (phospho-Tyr1173) LS-C6611
Specificity :
Recognizes the N1170AEpYLRV motif corresponding to the major autophosphorylation site of human EGF receptor. Does not cross-react with the non-phosphorylated human, mouse, rat and dog EGF receptor or with unrelated Tyr-phosphorylated proteins. Species cross-reactivity: mouse.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
AntigenModification :
pTyr1173
PresentationDesc :
PBS, 0.09% Sodium Azide, 40% Glycerol, Sucrose, PEG
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide corresponding to aa 1170-1176 (N1170AEpYLRV1176) of EGFR (epidermal growth factor receptor) phosphorylated at Tyr1173.
PurificationDesc :
Gel filtration
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
EGFR
StandardGeneSymbol :
EGFR
gene family :
Protein Kinase
Subfamily :
EGF Receptor
Reactivity :
Mouse, Dog, Rat, Human
Usage :
ELISA (0.05 µg/ml), IP (1 - 10 µg/10E6 cells), WB (1 µg/ml)
ShortWebDescription :
EGFR antibody LS-C6611 is an unconjugated mouse monoclonal antibody to EGFR (pTyr1173) from human. It is reactive with human, mouse, rat and other species. Validated for ELISA, IP and WB. Cited in 2 publications.
UsageText :
WB: For AP/BCIP/NBT (MTT) Detection:1 ug/ml. For HRPO/ECL deterction: 0.1 ug/ml. Use 0.5% Caseine, 0.5% BSA in PBST for blocking.
Synonyms :
EGFR, EGF Receptor, ERBB, ERBB1, MENA, PIG61, Proto-oncogene c-ErbB-1, V-erb-b homolog, EGF-R, HER1
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.