This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Cytokeratin 5+14 Antibody (C-Terminus, Ready-to-Use) LS-C64339
catalog :
LS-C64339
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
product information
AntibodyID :
64965
AntibodyName :
LS-C64339
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
Cytokeratin 5+14 Antibody (C-Terminus, Ready-to-Use) LS-C64339
Specificity :
This antibody cocktail reacts with cytokeratin 5 intermediate filament protein as well as to 50kD cytokeratin protein designated cytokeratin 14. Basal cells of human epidermis express acidic cytokeratin 14 and basic cytokeratin 5. Cytokeratin 5 is a 58kD protein, which is closely related to cytokeratin 6. Cytokeratin 5 and 6 are expressed in basal cell epithelioma, basal cells of prostate, urothelium, vagina, squamous cell carcinomas of skin, tongue, epiglottis and rectal-anal region. Cytokeratin 5 can be useful in the distinction of mesotheliomas from most adenocarcinomas. Cytokeratin 14 belongs to the type A (acidic) subfamily of low MW cytokeratins and exists in combination with cytokeratin 15. This antibody can be useful to distinguish stratified epithelial cells from simple epithelial cells. Species cross-reactivity: This antibody is reactive against human.
ClonalityDesc :
Monoclonal
AntibodyModification :
Ready-to-Use Unconjugated
AntigenModification :
C-Terminus
PresentationDesc :
PBS, pH 7.2, 0.08% sodium azide.
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Prokaryotic recombinant protein corresponding to 103 amino acid portion of C-Terminus of the human cytokeratin 5 molecule. LLLLL: Synthetic peptide of the extreme C-Terminus of human keratin-14.
PurificationDesc :
Purified
RecommendedStorageDesc :
Do not freeze. Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Freezing will result in a substantial loss of activity.
IsotypeName :
IgG1 + IgG3
Gene :
Cytokeratin 5+14
Reactivity :
Human
Usage :
ICC, IF, IHC, IHC-Fr
ShortWebDescription :
Cytokeratin 5+14 antibody LS-C64339 is an unconjugated mouse monoclonal antibody to human Cytokeratin 5+14 (C-Terminus). Validated for ICC, IF and IHC.
UsageText :
Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry (Fr) and Immunocytochemistry. Positive control: Skin.
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.