product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
HHV-8 ORF57 Antibody (C-Terminus) LS-C60137
catalog :
LS-C60137
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; human
Mariggiò G, Koch S, Zhang G, Weidner Glunde M, Rückert J, Kati S, et al. Kaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latency. PLoS Pathog. 2017;13:e1006335 pubmed publisher
product information
AntibodyID :
60607
AntibodyName :
LS-C60137
TargetSpecies :
Human Herpesvirus 8
Host Species :
Rabbit
Product Name :
HHV-8 ORF57 Antibody (C-Terminus) LS-C60137
Specificity :
A BLAST analysis was used to suggest cross-reactivity with ORF57 protein from human herpesvirus 8 types P and M sources based on 94% homology with the immunizing sequence. Reactivity against homologues from other sources is unknown.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
C-Terminus
PresentationDesc :
0.02 M Potassium Phosphate, pH 7.2, 0.15 M NaCl, 0.01% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the C-terminal of human KSHV ORF57 protein.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Aliquot and store at -20°C. Avoid freeze-thaw cycles. Store undiluted.
IsotypeName :
IgG
Gene :
HHV-8 ORF57
Reactivity :
Human, Human Herpesvirus 8
Usage :
ELISA (1:10000 - 1:70000), IHC, WB (1:5000 - 1:8000)
ShortWebDescription :
HHV-8 ORF57 antibody LS-C60137 is an unconjugated rabbit polyclonal antibody to HHV-8 ORF57 (C-Terminus) from human herpesvirus 8. It is reactive with human and human herpesvirus 8. Validated for ELISA, IHC and WB. Cited in 1 publication.
UsageText :
This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band 50-55 kD in size corresponding to KSHV ORF57 protein by western blotting in the appropriate cell lysate or extract.
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.