product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
THRA / THR Alpha Antibody LS-C60119
catalog :
LS-C60119
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 1
Reference
Aguiari P, Liu Y, Petrosyan A, Cheng S, Brent G, Perin L, et al. Persistent COUP-TFII expression underlies the myopathy and impaired muscle regeneration observed in resistance to thyroid hormone-alpha. Sci Rep. 2021;11:4601 pubmed publisher
product information
AntibodyID :
60589
AntibodyName :
LS-C60119
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
THRA / THR Alpha Antibody LS-C60119
Specificity :
This antibody reacts with human THRA protein. A BLAST analysis was used to suggest cross-reactivity with THRA from mouse, human and rat based on a 100% homology with the immunizing sequence. Cross-reactivity with THRA from other sources has not been determined.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
0.02 M Potassium Phosphate, pH 7.2, 0.15 M NaCl, 0.01% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the amino terminus of human THRA isoform 1 protein.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Short term: -20°C; Long term: -20°C.
IsotypeName :
IgG
Gene :
THRA / THR Alpha
StandardGeneSymbol :
THRA
gene family :
NHR
Subfamily :
NR1 Thyroid hormone-like
Reactivity :
Human
Usage :
ELISA (1:300000), IF (1:200), IHC (1:200), IP (1:100), WB (1:500 - 1:2000)
ShortWebDescription :
THR Alpha antibody LS-C60119 is an unconjugated rabbit polyclonal antibody to human THR Alpha (THRA). Validated for ELISA, IF, IHC, IP and WB. Cited in 1 publication.
UsageText :
This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~55 kD in size corresponding to THRA by western blotting in the appropriate cell lysate or extract. This antibody is capable of detecting transiently transfected THRA. Detection of endogenous THRA must be optimized by the end user.
Synonyms :
THRA, AR7, C-ERBA-1, C-erbaalpha, EAR-7.1/EAR-7.2, ERB-T-1, ERBA1, EAR-7, ERBA-related 7, HTR alpha 1, HTR alpha 2, THRA1, Thyroid hormone receptor alpha, T3R, Tralpha2, Triiodothyronine receptor, V-erbA-related protein 7, Thyroid hormone receptor, Tralpha1, NR1A1, THRA3, C-erbA-alpha, CHNG6, EAR7, ERBA, Erba-alpha, THRA2, TR alpha, Tralpha
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.