This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Leptin Antibody (clone 3G7) LS-C58410
catalog :
LS-C58410
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3G7

The same clone is also sold as:
reactivity :
human
product information
AntibodyID :
58880
AntibodyName :
LS-C58410
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
Leptin Antibody (clone 3G7) LS-C58410
Specificity :
Recognizes human leptin, a 16kD hormone that plays a key role in homeostasis, in energy intake and expenditure. It is produced by fat cells and the placenta. Leptin is a well known marker for obesity; the amount of leptin in the circulation correlates with the amount of fat tissue. Lack of functional leptin and leptin receptors lead to morbid obesity. However, leptin resistance is present in almost all obese humans, meaning that obesity is not necessarily due to a decrease in leptin, but rather to a decrease in the amount of leptin that reaches and binds to the leptin receptors in the hypothalamus. Leptin has also been implicated in a number of other processes including immune function, neuroendocrine function, the adaptive response to fasting, blood pressure, bone formation, blood cell development, glucose homeostasis, fatty acid metabolism and reproductive function. May be used as a capture antibody in ELISA assays for leptin.
ClonalityDesc :
Monoclonal
CloneName :
3G7
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant Leptin
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
Leptin
StandardGeneSymbol :
LEP
Reactivity :
Human
Usage :
ELISA
ShortWebDescription :
Leptin antibody LS-C58410 is an unconjugated mouse monoclonal antibody to human Leptin. Validated for ELISA.
UsageText :
ELISA: This product may be used in an indirect ELISA or as a capture antibody in a sandwich ELISA together with LS-C58411 as a detection reagent.
Synonyms :
LEP, Leptin, LEPD, Obese protein, Obese, mouse, homolog of, Obesity factor, OBS, OB
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.