This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
HPV16 E7 Antibody (clone 716-D1) LS-C58368
catalog :
LS-C58368
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
716-D1

The same clone is also sold as:
reactivity :
Human papillomavirus type 16
application :
western blot, ELISA
product information
AntibodyID :
58838
AntibodyName :
LS-C58368
TargetSpecies :
Virus
Host Species :
Mouse
Product Name :
HPV16 E7 Antibody (clone 716-D1) LS-C58368
Specificity :
Recognizes both the monomer and dimer forms of the E7 oncoprotein of human papilloma virus 16. Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Some HPV types are the causative agents of cervical cancer, with types 16 and 18 being particularly high-risk. The viral proteins E6 and E7 disrupts normal cell cycle regulation by interacting with p53 (a tumor-suppressing transcription factor) and Rb (retinoblastoma protein, also a tumor-suppressor). E7 particularly binds to Rb and histone deacetylases, resulting in activation of the E2F genes, which code for a family of transcription factors. The viral proteins E6 and E7 might be of particular interest in the development of therapeutic vaccines, since they are expressed early in viral infection. Reacts with both the monomer and dimer forms of the E7 protein of HPV-18.
ClonalityDesc :
Monoclonal
CloneName :
716-D1
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, less than 0.1% Sodium Azide
ImmunogenDesc :
Oncoprotein E7 from human papillomavirus 16.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG2a
Gene :
HPV16 E7
StandardGeneSymbol :
HPV16-E7
Reactivity :
Virus
Usage :
ELISA, WB
ShortWebDescription :
HPV16 E7 antibody LS-C58368 is an unconjugated mouse monoclonal antibody to virus HPV16 E7. Validated for ELISA and WB.
Synonyms :
HPV16-E7
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.