This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IL6 / Interleukin 6 Antibody (clone 6B4 IGH 54, Preservative Free) LS-C58341
catalog :
LS-C58341
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
6B4 IGH 54

The same clone is also sold as:
reactivity :
human, mouse
product information
AntibodyID :
58811
AntibodyName :
LS-C58341
TargetSpecies :
Mouse
Host Species :
Rat
Product Name :
IL6 / Interleukin 6 Antibody (clone 6B4 IGH 54, Preservative Free) LS-C58341
Specificity :
Specific for mouse IL-6 (interleukin-6), a multifunctional pro-inflammatory cytokine secreted by activated T cells, macrophages, endothelial cells, fibroblasts and osteoblasts, which acts as the principle inducer of the acute phase response in the liver. IL-6 signals through a membrane bound receptor complex consisting of the ligand-binding IL-6Ralpha chain (CD126) and the signal-transducing component gp130 (CD130), but can also stimulate cells expressing gp130 through a soluble IL-6R. IL-6 has been shown to stimulate B cell differentiation and subsequent immunoglobulin production, promote hybridoma growth, as well as regulating bone metabolism and stimulating energy mobilization in muscle and fatty tissue. Clone 6B4 IGH 54 can be used to neutralize the activity of 50pg/ml of recombinant mouse IL-6 by >95% in a functional assay.
ClonalityDesc :
Monoclonal
CloneName :
6B4 IGH 54
AntibodyModification :
Preservative Free Unconjugated
PresentationDesc :
PBS
ImmunogenDesc :
Natural partially purified mouse IL-6.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
IL6 / Interleukin 6
StandardGeneSymbol :
IL6
gene family :
Hormone
Reactivity :
Mouse
Usage :
ELISA
ShortWebDescription :
Interleukin 6 antibody LS-C58341 is an unconjugated rat monoclonal antibody to mouse Interleukin 6 (IL6). Validated for ELISA.
UsageText :
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Synonyms :
IL6, B-cell stimulatory factor 2, BSF-2, BSF2, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, Interleukin-6, Interleukin BSF-2, IFNB2, B-cell differentiation factor, CDF, HSF, IL-6
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.