This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Ly6A/E / Sca-1 Antibody (clone D7, FITC) LS-C58325
catalog :
LS-C58325
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
D7
reactivity :
Reclinomonas americana
application :
flow cytometry
product information
AntibodyID :
58795
AntibodyName :
LS-C58325
TargetSpecies :
Mouse
Host Species :
Rat
Product Name :
Ly6A/E / Sca-1 Antibody (clone D7, FITC) LS-C58325
Specificity :
Recognizes members of the lymphocyte activation protein-6 (Ly6) multigene family. Specifically recognizes Ly6A.2 and Ly6E.1. Ly6A/E is also known as stem cell antigen-1 (Sca-1). It is an 18kD mouse glycosyl phosphatidylinositol-anchored cell surface protein of the Ly6 gene family. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly6.1 and Ly6.2 allotypes. As such, it is the most common marker used for enriching adult hematopoietic stem cells. It has varied functions, it plays a role in bone formation, myoblast proliferation and differentiation and the activation and immunosuppressive function of T cells. Reported to induce T cell activation.
ClonalityDesc :
Monoclonal
CloneName :
D7
AntibodyModification :
FITC
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenType :
Cells
ImmunogenDesc :
IL-2-dependent mouse T cell line CTL-L
PurificationDesc :
Purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG2a
Gene :
Ly6A/E / Sca-1
Reactivity :
Mouse
Usage :
Flo (1:5 - 1:10)
ShortWebDescription :
Sca-1 antibody LS-C58325 is an FITC-conjugated rat monoclonal antibody to mouse Sca-1 (Ly6A / E). Validated for Flow.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.