This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
S100 Protein Antibody (clone 6G1) LS-C58307
catalog :
LS-C58307
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
reactivity :
human
application :
western blot, ELISA
product information
AntibodyID :
58777
AntibodyName :
LS-C58307
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
S100 Protein Antibody (clone 6G1) LS-C58307
Specificity :
Recognizes S100 protein derived from human brain tissue. It is a 21kD acidic calcium-binding protein synthesized by astroglial cells. It can be found predominantly as two isoforms, the alpha-beta heterodimer (S100a) and the beta-beta homodimer (S100b). The S100 family of proteins have been implicated in a large variety of intracellular and extracellular regulatory activities, such as cellular energy metabolism, cytoskeleton modification, cell proliferation and differentiation. When glial cells are damaged, S100 protein is leaked into the extracellular matrix and cerebrospinal fluid, further releasing into the bloodstream. As such, S100 protein can be used as a sensitive and reliable marker for nervous system damage, such as after brain damage or acute stroke. Recognizes both S100a (alpha-beta) and S100b (beta-beta). May be used to detect S100 protein in ELISA assay. Sensitive to EDTA and other bivalent-binding agents. Better performance can be obtained in the presence of 5 mM CaCl2 in assay buffers.
ClonalityDesc :
Monoclonal
CloneName :
6G1
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenDesc :
Human brain S100 protein.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
S100 Protein
Reactivity :
Human
Usage :
ELISA, WB
ShortWebDescription :
S100 Protein antibody LS-C58307 is an unconjugated mouse monoclonal antibody to human S100 Protein. Validated for ELISA and WB.
UsageText :
ELISA: This product may be used in an indirect ELISA or as a detection antibody in a sandwich ELISA together with LS-C58309 as a capture reagent.
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.
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