This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
PDPN / Podoplanin Antibody (clone D2-40, Concentrated) LS-C58138
catalog :
LS-C58138
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D2-40
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
AntibodyID :
58608
AntibodyName :
LS-C58138
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
PDPN / Podoplanin Antibody (clone D2-40, Concentrated) LS-C58138
Specificity :
Detects podoplanin (also known as D2-40), a type-I transmembrane mucoprotein, which is highly expressed in the placenta, lung and skeletal muscle. The function of podoplanin is yet to be elucidated; however, it may be involved in cell migration and/or actin cytoskeleton organisation. It is required for normal lung cell proliferation and alveolus formation at birth, and can induce platelet aggregation. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. Podoplanin is selectively expressed in lymphangiomas, Kaposi sarcomas, and a subset of angiosarcomas with probable lymphatic differentiation. Reported to be suitable for Western Blot.
ClonalityDesc :
Monoclonal
CloneName :
D2-40
AntibodyModification :
Concentrated Unconjugated
PresentationDesc :
PBS, 0.1% Sodium Azide, 1% BSA
ImmunogenType :
Recombinant protein
PurificationDesc :
Purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
PDPN / Podoplanin
StandardGeneSymbol :
PDPN
Reactivity :
Human
Usage :
IF, IHC, IHC-Fr (1:10 - 1:40), IHC-P (1:10 - 1:40), WB
ShortWebDescription :
Podoplanin antibody LS-C58138 is an unconjugated mouse monoclonal antibody to human Podoplanin (PDPN). Validated for IF, IHC and WB.
UsageText :
Immunohistology: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.
Synonyms :
PDPN, AGGRUS, HT1alpha-1, Glycoprotein 36, Glycoprotein, 36-KD, gp36, gp38, OTS8, PA2.26, PA2.26 antigen, Podoplanin, T1A, gp40, HT1A-1, HT1alpha-2, p38, T1-alpha, T1A-2
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.