This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
SIGLEC7 / CD328 Antibody (clone 5-386, RPE) LS-C58034
catalog :
LS-C58034
clonality :
monoclonal
host :
mouse
conjugate :
RPE
clone name :
5-386

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
product information
AntibodyID :
58504
AntibodyName :
LS-C58034
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
SIGLEC7 / CD328 Antibody (clone 5-386, RPE) LS-C58034
Specificity :
Specific for human CDw328, a type I transmembrane glycoprotein and member of the Siglec (sialic acid binding Ig-like lectin) family, designated Siglec-7, originally identified as an inhibitory NK cell receptor (NKR) and negative regulator of NK activation, attributed to ITIM recruitment of SHP-1 phosphatase. CDw328 is expressed predominantly by natural killer cells (NK) and to a lesser extent by monocytes and granulocytes and, like Siglec-5 (CD170), has been shown to bind to sialylated ligands of targets through recognition of sialic acid in both the alpha-2,3- and alpha-2,6- glycosidic linkage.
ClonalityDesc :
Monoclonal
CloneName :
5-386
AntibodyModification :
RPE
PresentationDesc :
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
ImmunogenType :
Cells
ImmunogenDesc :
Monocyte-derived dendritic cells
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
ResuspensionLiquidDesc :
Use 1 ml of sterile Distilled water.
IsotypeName :
IgG1
Gene :
SIGLEC7 / CD328
StandardGeneSymbol :
SIGLEC7
gene family :
Immunoglobulin
Reactivity :
Human
Usage :
Flo (1:1)
ShortWebDescription :
CD328 antibody LS-C58034 is an RPE-conjugated mouse monoclonal antibody to human CD328 (SIGLEC7). Validated for Flow.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Method sheets are available on request.
Synonyms :
SIGLEC7, AIRM-1, AIRM1, CD328 antigen, CDw328, CD328, D-siglec, QA79, SIGLEC-7, QA79 membrane protein
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.