This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CD58 Antibody (Cytoplasmic Domain, clone MEM-63, APC) LS-C57686
catalog :
LS-C57686
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
MEM-63

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
product information
AntibodyID :
58156
AntibodyName :
LS-C57686
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
CD58 Antibody (Cytoplasmic Domain, clone MEM-63, APC) LS-C57686
Specificity :
CD58, or LFA-3, is a membrane glycoprotein of 55-70kD. It occurs in two forms, one transmembrane with a cytoplasmic domain, the other form anchored in the membrane via a glycosylphosphatidylinositol tail. The complete amino acid sequence of both forms has been deduced from cDNA. It is heavily N-glycosylated. CD58 is a cell adhesion molecule which plays a critical role in facilitation of antigen specific recognition through interaction with CD2 on T lymphocytes. It is a member of the immunoglobulin superfamily of molecules. CD58 has a wide tissue distribution, being present on erythrocytes, platelets, monocytes, a subset of lymphocytes, bone marrow cells, epithelium and endothelial cells. There are approximately 5000 CD58 molecules on each erythrocyte. There is reduced expression of CD58 on hemopoietic cells in individuals with paroxysmal nocturnal hemoglobinuria.
ClonalityDesc :
Monoclonal
CloneName :
MEM-63
AntibodyModification :
APC
AntigenModification :
Cytoplasmic Domain
PresentationDesc :
TBS, 0.09% Sodium Azide
ImmunogenType :
Recombinant protein
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
ResuspensionLiquidDesc :
Reconstitute with distilled water.
IsotypeName :
IgG1
Gene :
CD58
StandardGeneSymbol :
CD58
gene family :
Immunoglobulin
Reactivity :
Human
Usage :
Flo (1:1 - 1:10)
ShortWebDescription :
CD58 antibody LS-C57686 is an APC-conjugated mouse monoclonal antibody to human CD58 (Cytoplasmic Domain). Validated for Flow.
UsageText :
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Synonyms :
CD58, CD58 antigen, AG3, LFA-3, LFA3, Surface glycoprotein LFA-3, Surface glycoprotein lfa3, CD58 molecule
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.