This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Basigin / Emmprin / CD147 Antibody (clone MEM-M6/1, APC) LS-C57534
catalog :
LS-C57534
clonality :
monoclonal
host :
mouse
conjugate :
APC
reactivity :
human
application :
flow cytometry
product information
AntibodyID :
58004
AntibodyName :
LS-C57534
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
Basigin / Emmprin / CD147 Antibody (clone MEM-M6/1, APC) LS-C57534
Specificity :
Recognizes the human CD147 cell surface antigen, also known as Basigin, EMMPRIN and collagenase stimulatory factor. CD147 is a 385 amino acid single pass type 1 trans-membrane glycoprotein bearing 3 potential N-glycosylation sites, a single N-terminal (distal) and a more proximal in its extracellular region. Was raised and screened against recombinant extracellular region of huCD147 expressed in CHO cells, along with a number of other MEM-M6 clones. Epitope mapping indicates that clone MEM-M6/1 binds to an epitope within the distal Ig-like C-2 type domain. This is confirmed by flow cytometric studies using beads coated with constructs containing only the distal Ig-like or proximal Ig-like domains. Binds to both un-stimulated and phytohemagglutinin (PHA) stimulated (activated) T lymphocytes with levels of CD147 enhanced following PHA stimulation. CD147 is also expressed by peripheral blood and endothelial cells as well as many cultured cells of hematopoietic and non-hematopoietic origin.
ClonalityDesc :
Monoclonal
CloneName :
MEM-M6/1
AntibodyModification :
APC
PresentationDesc :
PBS, 0.09% Sodium Azide, 1% BSA
ImmunogenType :
Recombinant protein
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
ResuspensionLiquidDesc :
Reconstitute with distilled water.
IsotypeName :
IgG1
Gene :
Basigin / Emmprin / CD147
StandardGeneSymbol :
BSG
Reactivity :
Human
Usage :
Flo (1:1)
ShortWebDescription :
CD147 antibody LS-C57534 is an APC-conjugated mouse monoclonal antibody to human CD147 (Basigin / Emmprin). Validated for Flow.
UsageText :
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells or 100 ul whole blood. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Synonyms :
BSG, 5F7, Basigin, Basigin (Ok blood group), CD147 antigen, EMMPRIN, OK, OK blood group antigen, TCSF, CD147, M6
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.