This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
DISC1 Antibody LS-C56896
catalog :
LS-C56896
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry - frozen section
product information
AntibodyID :
57366
AntibodyName :
LS-C56896
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
DISC1 Antibody LS-C56896
Specificity :
Recognizes disrupted in schizophrenia 1 (DISC1), ~93 kD protein located in the nucleus, cytoplasm and mitochondria. The DISC1 protein is widely expressed in normal tissues. It is involved in neurite outgrowth and cortical development through its interaction with a variety of proteins including lissencephaly-1 (LIS1), NudeE-like (NUDEL) and phosphodiesterase 4B. In certain cases of schizophrenia the DISC1 gene has been found to be disrupted by a t(1;11) (q42.1;q14.3) translocation, and studies suggest that DISC1 could be a candidate susceptibility gene for this condition. Has been found suitable for immunocytochemistry (ICC) at a concentration of 5 ug/ml.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.02% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
An 18 amino acid peptide located near the centre of human DISC1.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG
Gene :
DISC1
StandardGeneSymbol :
DISC1
Reactivity :
Human
Usage :
IHC-Fr, WB (1 - 2 µg/ml)
ShortWebDescription :
DISC1 antibody LS-C56896 is an unconjugated rabbit polyclonal antibody to human DISC1. Validated for IHC and WB.
UsageText :
Western Blot: LS-C56896 detects bands of approximately 95-100kD in SK-N-SH cell lysate.
Synonyms :
DISC1, C1orf136, Disrupted in schizophrenia 1, KIAA0457, SCZD9
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.