product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
TLR3 Antibody (clone 40C1285.6) LS-C545
catalog :
LS-C545
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
40C1285.6
reactivity :
human
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 3
Published Application/Species/Sample/DilutionReference
  • western blot; human
Cao Z, Guo K, Zheng M, Ning P, Li H, Kang K, et al. A comparison of the impact of Shimen and C strains of classical swine fever virus on Toll-like receptor expression. J Gen Virol. 2015;96:1732-45 pubmed publisher
Snyder J, Wood T, Corry K, Moralejo D, Parikh P, Juul S. Ontogeny of white matter, toll-like receptor expression, and motor skills in the neonatal ferret. Int J Dev Neurosci. 2018;70:25-33 pubmed publisher
Cao Z, Zheng M, Lv H, Guo K, Zhang Y. Tissue expression of Toll-like receptors 2, 3, 4 and 7 in swine in response to the Shimen strain of classical swine fever virus. Mol Med Rep. 2018;17:7122-7130 pubmed publisher
product information
AntibodyID :
2767
AntibodyName :
LS-C545
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
TLR3 Antibody (clone 40C1285.6) LS-C545
Specificity :
KLH-conjugated synthetic peptide of human TLR3.
ClonalityDesc :
Monoclonal
CloneName :
40C1285.6
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.05% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A synthetic peptide corresponding to amino acids 55-70 (VLNLTHNQLRRLPAAN)of human TLR3 was used as immunogen, Gen Bank no. gb AAH59372.1 . Human TLR3 is an 870 amino acid protein. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Ferret, Sheep, Goat (100%); Chimpanzee, Dog, Bovine, Panda, Pig, Zebu, Guinea pig (94%); Mouse, Rat, Cat, Bat, Elephant (88%); Horse, Rabbit, Opossum (81%).
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
TLR3
StandardGeneSymbol :
TLR3
gene family :
Toll-like Receptor
Reactivity :
Goat, Sheep, Human, Monkey
Usage :
Flo, IHC, IHC-P, IP, WB (1 - 3 µg/ml)
ShortWebDescription :
TLR3 antibody LS-C545 is an unconjugated mouse monoclonal antibody to TLR3 from human. It is reactive with human, goat, monkey and other species. Validated for Flow, IHC, IP and WB. Cited in 3 publications.
Synonyms :
TLR3, CD283, Toll-like receptor 3, CD283 antigen, IIAE2
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.