product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
AGTR1 / AT1 Receptor Antibody (Internal Region) LS-C54459
catalog :
LS-C54459
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; human
Li D, Wang Q, Zhang Y, Li D, Yang D, Wei S, et al. A Novel Swine Model of Spontaneous Hypertension With Sympathetic Hyperactivity Responds Well to Renal Denervation. Am J Hypertens. 2016;29:63-72 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-C54459 image 1
Antibody (0.3 ug/ml) staining of Mouse Liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
product information
AntibodyID :
54918
AntibodyName :
LS-C54459
TargetSpecies :
Human
Host Species :
Goat
Product Name :
AGTR1 / AT1 Receptor Antibody (Internal Region) LS-C54459
Specificity :
All reported variants represent identical protein (NP_000676.1, NP_004826.2, NP_033611.1, NP_114038.1 and NP_114438.1).
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
Internal Region
PresentationDesc :
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
ImmunogenDesc :
Peptide with sequence C-EIQKNKPRNDDIFK, from the Internal region of the protein sequence according to NP_000676.1; NP_004826.2; NP_033611.1; NP_114038.1; NP_114438.1.
PurificationDesc :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
RecommendedStorageDesc :
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Gene :
AGTR1 / AT1 Receptor
BlockingPeptide :
LS-E26180
StandardGeneSymbol :
AGTR1
gene family :
GPCR
Subfamily :
Angiotensin
Reactivity :
Mouse, Human
Usage :
Peptide-ELISA (1:32000 Detection Limit), WB (0.1 - 0.3 µg/ml)
ShortWebDescription :
AT1 Receptor antibody LS-C54459 is an unconjugated goat polyclonal antibody to AT1 Receptor (AGTR1) (Internal Region) from human. It is reactive with human and mouse. Validated for Peptide-ELISA and WB. Cited in 1 publication.
UsageText :
Western Blot: Approx 38kDa band observed in Human and Mouse Liver lysates (calculated MW of 41.1kDa according to Human NP_000676.1 and 40.9kDa according to Mouse NP_796296.1) Additional bands of unknown identity were also observed at 45 and 75kDakDa and were successfully blocked by incubation with the immunizing peptide. Primary incubation 1 hour at room temperature. Preliminary testing was unsuccessful on Rat Liver.
Synonyms :
AGTR1, AG2S, AGTR1A, AGTR1B, Angiotensin II type-1 receptor, Ang ii receptor type 1a, Angiotensin receptor 1, Angiotensin receptor 1a, Angiotensin receptor 1B, AT1R, AT1 receptor, At1a receptor, AT1B, AT1AR, AT2R1, AT2R1A, AT2R1B, HAT1R, AT1, At1a, At1b receptor, AT1BR, Type-1 angiotensin II receptor
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.